Volumen plaquetario medio en el segundo trimestre del embarazo como predictor de preeclampsia

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Autores

Eduardo Reyna-Villasmil
Jorly Mejía Montilla
Duly Torres Cepeda
Nadia Reyna-Villasmil
Martha Rondón Tapia

Resumen


Objetivo: establecer la utilidad de los valores del volumen plaquetario medio en el segundo trimestre del embarazo como predictor del desarrollo de preeclampsia. Materiales y métodos: investigación prospectiva en 504 pacientes nulíparas con embarazos simples entre 17 y 20 semanas que acudieron a la consulta prenatal. Se evaluaron las características generales, valores del volumen plaquetario medio y eficacia pronóstica. Resultados: los casos fueron 41 embarazadas que desarrollaron preeclampsia (grupo A) y 463 embarazadas consideradas controles (grupo B). No se encontraron diferencias estadísticas significativas en la edad materna, edad gestacional y presión arterial sistólica y diastólica al momento de la realización de la ecografía (p = ns). La edad gestacional al momento del diagnóstico de preeclampsia en el grupo A fue de 35,0 +/- 3,2 semanas. Se encontraron diferencias estadísticamente significativas en los valores del volumen plaquetario medio entre el grupo A (10,15 +/- 0,57 fL) y el B (9,65 +/- 0,61 fL; p < 0,0001). Un valor de corte de 9,50 fL presentó una cifra por debajo de la curva de 0,714 y tiene sensibilidad de 85,4%, especificidad del 40,6%, valor predictivo positivo del 11,3% y valor predictivo negativo del 96,5%. Conclusión: los valores del volumen plaquetario medio en el segundo trimestre no son útiles en la predicción del desarrollo de preeclampsia.

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Referencias

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