Gliomas difusos en áreas elocuentes: avances diagnósticos y terapéuticos
Diffuse gliomas within eloquent areas: diagnostic and therapeutic advances
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Objetivo: presentar los avances diagnósticos, moleculares y radiológicos, así como en las estrategias terapéuticas para gliomas difusos en los últimos 5 años (2018-2023) en la Fundación Universitaria de Ciencias de la Salud (FUCS), Bogotá D.C., Colombia. Materiales y métodos: se describen las técnicas diagnósticas y terapéuticas utilizadas para gliomas difusos con casos ilustrativos. Resultados: se muestran los avances de las herramientas diagnósticas y terapéuticas para el manejo de gliomas difusos. Discusión: en los últimos 5 años se ha avanzado en la clasificación, diagnóstico y tratamiento de los gliomas difusos, gracias a los avances tecnológicos como los marcadores moleculares, la tractografía y la fusión de imágenes para la neuronavegación y las técnicas de estimulación cortical. Esto ha permitido que el tratamiento de los pacientes con dichos tumores mejore la tasa de morbilidad, la calidad de vida libre de enfermedad y la supervivencia global. Conclusiones: las técnicas de diagnóstico como la tractografía, la fusión integral de imágenes intraoperatorias y el mapeo cerebral electrofisiológico con estimulación cortical y subcortical han mejorado el diagnóstico y tratamiento de los gliomas difusos.
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Weller M, Wick W, Aldape K, Brada M, Berger M, Pfister SM, et al. Glioma. Nat Rev Dis Primers. 2015;1:15017. https://doi.org/10.1038/nrdp.2015.17 DOI: https://doi.org/10.1038/nrdp.2015.17
Louis DN, Perry A, Wesseling P, Brat DJ, Cree IA, Figarella-Branger D, et al. The 2021 WHO Classification of Tumors of the Central Nervous System: a summary. Neuro Oncol. 2021;23(8):1231-1251. https://doi.org/10.1093/neuonc/noab106. DOI: https://doi.org/10.1093/neuonc/noab106
Ordonez-Rubiano EG, Johnson J, Enciso-Olivera CO, Marin-Munoz JH, Cortes-Lozano W, Baquero-Herrera PE, et al. Reconstruction of the Ascending Reticular Activating System with Diffusion Tensor Tractography in Patients with a Disorder of Consciousness after Traumatic Brain Injury. Cureus. 2017;9(9):e1723. https://doi.org/10.7759/cureus.1723. DOI: https://doi.org/10.7759/cureus.1723
Ordonez-Rubiano EG, Valderrama-Arias FA, Forbes JA, Johnson JM, Younus I, Marin-Munoz JH, et al. Identification of Preoperative Language Tracts for Intrinsic Frontotemporal Diseases: A Pilot Reconstruction Algorithm in a Middle-Income Country. World Neurosurg. 2019;125:e729-e742. https://doi.org/10.1016/j.wneu.2019.01.163. DOI: https://doi.org/10.1016/j.wneu.2019.01.163
Parra-Morales AM, Rudas J, Vargas JA, Gomez F, Enciso-Olivera CO, Trujillo-Rodriguez D, et al. Structural and functional connectivity of ascending reticular activating system in a patient with impaired consciousness after a cardiac arrest: A case report. Medicine (Baltimore). 2019;98(19):e15620. https://doi.org/10.1097/MD.0000000000015620. DOI: https://doi.org/10.1097/MD.0000000000015620
Enciso-Olivera CO, Ordonez-Rubiano EG, Casanova-Libreros R, Rivera D, Zarate-Ardila CJ, Rudas J, et al. Structural and functional connectivity of the ascending arousal network for prediction of outcome in patients with acute disorders of consciousness. Sci Rep. 2021;11(1):22952. https://doi.org/10.1038/s41598-021-98506-7. DOI: https://doi.org/10.1038/s41598-021-98506-7
Abdala-Vargas NJ, Umana GE, Patino-Gomez JG, Ordonez-Rubiano E, Cifuentes-Lobelo HA, Palmisciano P, et al. Standardization of Strategies to Perform a Parafascicular Tubular Approach for the Resection of Brain Tumors in Eloquent Areas. Brain Sci. 2023;13(3):498. https://doi.org/10.3390/brainsci13030498. DOI: https://doi.org/10.3390/brainsci13030498
Penfield W, Baldwin M. Temporal lobe seizures and the technic of subtotal temporal lobectomy. Ann Surg. 1952;136(4):625-634.
Spencer DD, Spencer SS. Surgery for epilepsy. Neurol Clin. 1985;3(2):313-330. DOI: https://doi.org/10.1016/S0733-8619(18)31039-9
Vadera S, Kshettry VR, Klaas P, Bingaman W. Seizure-free and neuropsychological outcomes after temporal lobectomy with amygdalohippocampectomy in pediatric patients with hippocampal sclerosis. J Neurosurg Pediatr. 2012;10(2):103-107. https://doi.org/10.3171/2012.4.PEDS1233. DOI: https://doi.org/10.3171/2012.4.PEDS1233
Yeh FC, Zaydan IM, Suski VR, Lacomis D, Richardson RM, Maroon JC, et al. Differential tractography as a track-based biomarker for neuronal injury. Neuroimage. 2019;202:116131. https://doi.org/10.1016/j.neuroimage.2019.116131. DOI: https://doi.org/10.1016/j.neuroimage.2019.116131
Henderson F, Abdullah KG, Verma R, Brem S. Tractography and the connectome in neurosurgical treatment of gliomas: the premise, the progress, and the potential. Neurosurg Focus. 2020;48(2):E6. https://doi.org/10.3171/2019.11.FOCUS19785. DOI: https://doi.org/10.3171/2019.11.FOCUS19785
Duffau H. Surgical neurooncology is a brain networks surgery: a "connectomic" perspective. World Neurosurg. 2014;82(3-4):e405-7. https://doi.org/10.1016/j.wneu.2013.02.051. DOI: https://doi.org/10.1016/j.wneu.2013.02.051
Jensen JH, Helpern JA, Ramani A, Lu H, Kaczynski K. Diffusional kurtosis imaging: the quantification of non-gaussian water diffusion by means of magnetic resonance imaging. Magn Reson Med. 2005;53(6):1432-40. https://doi.org/10.1002/mrm.20508. DOI: https://doi.org/10.1002/mrm.20508
Khalsa SSS, Hollon TC, Adapa A, Urias E, Srinivasan S, Jairath N, et al. Automated histologic diagnosis of CNS tumors with machine learning. CNS Oncol. 2020;9(2):CNS56. https://doi.org/10.2217/cns-2020-0003. DOI: https://doi.org/10.2217/cns-2020-0003
Li YC, Chiu HY, Lin YJ, Chen KT, Hsu PW, Huang YC, et al. The Merits of Awake Craniotomy for Glioblastoma in the Left Hemispheric Eloquent Area: One Institution Experience. Clin Neurol Neurosurg. 2021;200:106343. https://doi.org/10.1016/j.clineuro.2020.106343. DOI: https://doi.org/10.1016/j.clineuro.2020.106343
Hervey-Jumper SL, Li J, Lau D, Molinaro AM, Perry DW, Meng L, et al. Awake craniotomy to maximize glioma resection: methods and technical nuances over a 27-year period. J Neurosurg. 2015;123(2):325-39. https://doi.org/10.3171/2014.10.JNS141520. DOI: https://doi.org/10.3171/2014.10.JNS141520
Zhang JJY, Lee KS, Voisin MR, Hervey-Jumper SL, Berger MS, Zadeh G. Awake craniotomy for resection of supratentorial glioblastoma: a systematic review and meta-analysis. Neurooncol Adv. 2020;2(1):vdaa111. https://doi.org/10.1093/noajnl/vdaa111. DOI: https://doi.org/10.1093/noajnl/vdaa111
Orringer DA, Pandian B, Niknafs YS, Hollon TC, Boyle J, Lewis S, et al. Rapid intraoperative histology of unprocessed surgical specimens via fibre-laser-based stimulated Raman scattering microscopy. Nat Biomed Eng. 2017;1: 0027. https://doi.org/10.1038/s41551-016-0027. DOI: https://doi.org/10.1038/s41551-016-0027
Jonsson P, Lin AL, Young RJ, DiStefano NM, Hyman DM, Li BT, et al. Genomic Correlates of Disease Progression and Treatment Response in Prospectively Characterized Gliomas. Clin Cancer Res. 2019;25(18):5537-5547. https://doi.org/10.1158/1078-0432.CCR-19-0032. DOI: https://doi.org/10.1158/1078-0432.CCR-19-0032
Lv H, Wang Z, Tong E, Williams LM, Zaharchuk G, Zeineh M, et al. Resting-State Functional MRI: Everything That Nonexperts Have Always Wanted to Know. AJNR Am J Neuroradiol. 2018;39(8):1390-1399. https://doi.org/10.3174/ajnr.A5527. DOI: https://doi.org/10.3174/ajnr.A5527
Cargnelutti E, Ius T, Skrap M, Tomasino B. What do we know about pre- and postoperative plasticity in patients with glioma? A review of neuroimaging and intraoper ative mapping studies. Neuroimage Clin. 2020;28:102435. https://doi.org/10.1016/j.nicl.2020.102435. DOI: https://doi.org/10.1016/j.nicl.2020.102435