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A pesar de ser una patología con tan baja incidencia, la fascitis necrosante (FN) es importante por sus severas secuelas y elevada tasa de mortalidad. Esta revisión busca ampliar los conocimientos básicos de una enfermedad cuya fisiopatología apenas comienza a ser dilucidada. Existe la falsa creencia de que su devastador comportamiento es secundario a la agresividad de los gérmenes implicados en su etiología, sin embargo su evolución implacable se debe en esencia a la disminución en la perfusión de los tejidos comprometidos, como efecto de la cascada inflamatoria localizada en las fascias que son un espacio desde el punto de vista anatómico susceptible a los cambios de presión tisular. Nuestra revisión busca aclarar conceptos erróneos mediante la exposición detallada de la epidemiología, fisiopatología, clínica, diagnóstico y tratamiento, brindando elementos de valor para que todo el personal médico tanto de pregrado, como profesionales de la salud generales y especialistas, adquiera la capacidad de identificarla y manejarla tempranamente, logrando con ello un importante impacto en su mortalidad. Abreviaturas: FN, Fascitis necrosante.
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