El sistema de la proteína C activada en el cuadro séptico

The effects of activated protein C on the sepsis syndrome

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Carlos Hugo Escobar Soto


Durante los últimos años y con el advenimiento del conocimiento y las técnicas de biología molecular, las concepciones fisiopatológicas del cuadro séptico han cambiado en forma dramática. Prueba de ello es la aprobación del empleo de formas recombinantes de la proteína C activada por parte de la Administración Federal de Alimentos y Medicamentos de Estados Unidos (FDA). Con la presente revisión se pretende hacer un análisis del estado general del conocimiento respecto al papel que la proteína C activada y su sistema de respuesta cumplen en el contexto del cuadro séptico.

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