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En la práctica pediátrica y neonatal cada día sube la frecuencia de recién nacidos con mayor prematurez que requieren cuidados especiales dadas sus condiciones de base, con el fin de mejorar la sobrevida y disminuir las morbilidades a largo plazo. La nutrición utilizando el aparato digestivo en estos pacientes ha sido un reto importante y cambiante en el enfoque que se da a la misma, pues se ha relacionado con patologías específicas y se ha demostrado que mejorán dola disminuiremos de manera importante las complicaciones futuras. Hay que tener en cuenta que la nutrición en el período neonatal tiene inferencia en el desarrollo y salud posterior del individuo en la edad adulta.
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