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Encefalitis autoinmune: experiencia de una serie de casos

Autoinmune encephalitis: a series of cases




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Mariño, N., Triana, J., Nieto, V., Paul Vergara, J., Silva, M., & Palacios, E. (2019). Encefalitis autoinmune: experiencia de una serie de casos. Revista Repertorio De Medicina Y Cirugía, 28(1). https://doi.org/10.31260/RepertMedCir.v28.n1.2019.876

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Esta obra está bajo una licencia internacional Creative Commons Atribución-NoComercial-CompartirIgual 4.0.

Nathalie Mariño
    Javier Triana
      Víctor Nieto
        Jean Paul Vergara
          Miguel Silva
            Eduardo Palacios

              La encefalitis límbica autoinmune se define como un desorden inflamatorio severo en el cerebro que genera una encefalopatía rápidamente progresiva por lo regular en menos de 6 semanas. Se han descrito anticuerpos contra epítopes de proteínas sinápticas de superficie o contra proteínas intracelulares. Se reportan seis casos de encefalitis autoinmune con la descripción de cada uno incluyendo las manifestaciones típicas, alteraciones imagenológicas, curso clínico, complicaciones durante la hospitalización y respuesta al tratamiento. En dos de los casos se logró confirmar mediante el aislamiento de los anticuerpos. Uno falleció durante su hospitalización. Nuestra experiencia muestra un alto riesgo de secuelas y refractariedad al tratamiento que dependen del tiempo   de inicio de la terapia.


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