Cómo citar
Erazo NarvaezA. F., Díez ChamorroL. S., Ordoñez RuizG. A., & Niño CastañoV. E. (2020). Meningoencefalitis por herpes simple: una visión de la infección viral que causa el mayor compromiso cerebral. Revista Repertorio De Medicina Y Cirugía, 29(3), 148-156. https://doi.org/10.31260/RepertMedCir.01217273.939

Autores/as

Andres Felipe Erazo Narvaez, Dr
Universidad del Cauca
Bio
Leon Santiago Díez Chamorro, Dr
Universidad del Cauca
Bio
Giovanni Andres Ordoñez Ruiz, Dr
Universidad del Cauca
Bio
Victoria Eugenia Niño Castaño, Dr
Universidad del Cauca
Bio

Resumen

La inflamación del sistema nervioso central secundaria a la infección por la familia herpesviridae puede generar un compromiso difuso del parénquima encefálico, la cual puede ser fatal en ausencia de un rápido diagnóstico y tratamiento. Objetivo: revisar las diferentes características biológicas, fisiopatológicas, clínicas, terapéuticas y pronóstico de la meningoencefalitis causada por VHS-1 y 2. Materiales y métodos: revisión de la literatura científica (revisión crítica), llevada a cabo mediante las bases de datos Medline y buscadores específicos IMBIOMED, PUBMEDE, SCIENCEDIRECT, SCIELO, con un total de 150 artículos, se priorizaron 67 los cuales fueron leídos a profundidad. Resultados y discusión: debido el neurotropismo del herpes virus simple puede causar neuroinvasividad, neurotoxicidad y latencia en el SNC. Por sus características semiológicas inespecíficas se requiere un estudio exhaustivo para lograr el diagnóstico acertado. Los métodos actuales tales como neuroimágenes y PCR han aportado al esclarecimiento del diagnóstico etiológico de esta patología. La detección temprana de la entidad y la instauración precoz del tratamiento, se asocian con un aumento en la tasa de supervivencia y a una disminución de las secuelas neurológicas. Conclusión: conocer la biología del virus, su comportamiento, las características clínicas y el tratamiento de la entidad es una estrategia eficaz para disminuir secuelas y desenlaces fatales.

Licencia

Creative Commons License
Esta obra está bajo licencia internacional Creative Commons Reconocimiento-NoComercial-SinObrasDerivadas 4.0.

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Coordinador Editorial

Leonardo Arismendy Rodriguez
jlarismendy@fucsalud.edu.co
Fundación Universitaria de Ciencias de la Salud - FUCS
Bogotá DC, Colombia
Dirección: Carrera 19 No. 8 A 32
Tel: (+571) 3538100 Ext. 2836

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Gloria Restrepo B.
revista.repertorio@fucsalud.edu.co
Fundación Universitaria de Ciencias de la Salud - FUCS
Bogotá DC, Colombia
Dirección: Carrera 19 No. 8 A 32
Tel: (+571) 3538100 Ext. 2836


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