Characterisation of patients with delayed bloodstream infections in the Neonatal Unit of San José Hospital between June 2014 and May 2015. A case series

Caracterización de los pacientes con infección tardía del torrente sanguíneo en la Unidad Neonatal del Hospital de San José entre junio de 2014 y mayo de 2015. Serie de casos

Introduction: Bloodstream infections (BSIs) is an important cause of morbidity, mortality, and sequelae in the neonate in neonatal care units (NICUs).
Objective: To present a profile of patients admitted to the NICU of the Hospital de San José de Bogotá in the period between June 2014 and May 2015.
Materials and methods: The study included a series of patients with a positive blood culture after 72 hours of life, and with an age of less than 28 days upon arrival. Those with blood cultures suggestive of contamination were excluded. A descriptive analysis was performed to describe the relevant demographic and clinical variables in the literature for BSIs, as well as outcomes, such as stay and mortality.
Results: Of the 25 cases included, 48% were admitted due to respiratory disorders, 24% for major malformations, and 12% for prematurity. The median gestational age was 32 weeks (RIQ 29-38), with a median weight of 1555 g (RIQ 990-2515). Invasive mechanical ventilation was required in 75% of cases, and 88% used nasogastric tube. Around three-quarters (76%) received parenteral nutrition, and 40% received intravenous corticosteroids. An umbilical catheter was inserted in 48% of patients, a femoral catheter in 16%, and 92% had peripherally inserted central catheter. The isolates found were mainly Klebsiella (40%) and Staphylococcus (44%). Mortality was 20%.
Conclusions: The characteristics found in this group establish the risk factors that match the information in the literature for the presentation of late STIs by multiresistant microorganisms.

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