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Tumor and non-tumor mediated hypoglycemia by pancreatic beta cells, a diagnostic challenge

Hipoglucemia tumoral dependiente y no dependiente de células β-pancreáticas, un reto diagnóstico




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Case Reports

How to Cite
Altamar LLanos, H. ., Sánchez Márquez, P. E., Lizcano Losada, F. ., Omeara, . M. A. ., Valenzuela Rincón, A. ., García Sanchez, R. ., & Martínez Rosales, F. J. . (2021). Tumor and non-tumor mediated hypoglycemia by pancreatic beta cells, a diagnostic challenge. Journal of Medicine and Surgery Repertoire, 30(1), 59-63. https://doi.org/10.31260/RepertMedCir.01217372.1075

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Henry Altamar LLanos
    Pedro Enrique Sánchez Márquez
      Fernando Lizcano Losada
        Miguel Augusto Omeara
          Alex Valenzuela Rincón
            Rafael García Sanchez
              Freddy Jesus Martínez Rosales

                Henry Altamar LLanos,

                Medicina Interna, Universidad El Bosque, Endocrinología Universidad del Rosario, Bogotá D.C., Colombia


                Pedro Enrique Sánchez Márquez,

                Endocrinología, Grupo COD2, Clínica de las Américas, Medellín, Colombia


                Fernando Lizcano Losada,

                Medicina Interna, Universidad El Bosque, Endocrinología Universidad del Rosario, Bogotá D.C., Colombia


                Miguel Augusto Omeara,

                Medicina Interna, Universidad El Bosque, Endocrinología Universidad del Rosario, Bogotá D.C., Colombia


                Alex Valenzuela Rincón,

                Medicina Interna, Universidad El Bosque, Endocrinología Universidad del Rosario, Bogotá D.C., Colombia


                Rafael García Sanchez,

                Medicina Interna, Universidad de La Sabana. Bogotá D.C., Colombia


                Freddy Jesus Martínez Rosales,

                Medicina Interna, Universidad Libre. Bogotá D.C., Colombia


                Hypoglycemia is a common medical emergency which is mostly secondary to the use of oral or injected hypoglycemic drugs indicated in patients with diabetes mellitus. However, it can present spontaneously and severely in relation to multiple clinical conditions, including neoplasms. When faced with hypoglycemia associated with paraneoplastic disorders, the pathophysiological mechanisms of hypoglycemia must be recognized and a timely and accurate diagnosis must be established in order to diminish complications inherent to this clinical syndrome. We herein present two patients with hypoglycemia refractory to initial medical management, sharing similar appearance with other pathologies. The first case corresponds to a patient with an insulinoma and the second to a patient with a hemangiopericytoma.


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