Rupture of hepatic hematoma secondary to neural therapy

Ruptura de hematoma hepático secundario a terapia neural

Objective: to determine whether neural therapy is a treatment option which can be used without the occurrence of adverse effects. Case report: we present and analyze the case of a female patient who was admitted to the emergency room for generalized abdominal pain. A hepatic hematoma was diagnosed, and a review of the scientific literature was conducted. Results: a laparotomy with damage control surgery was performed, obtaining satisfactory outcomes, with hospital discharge without any added complications. Conclusions: neural therapy is a treatment for which there is not enough scientific evidence to support its safety in patients.

1. Weinschenk S. Neural therapy - A review of the therapeutic use of local anesthetics. Acupuncture and Related Therapies 2012;1(1):59. https://doi.org/10.1016/j.arthe.2012.12.004.
2. Egli S, Pfister M, Ludin SM, Puente de la Vega K, Busato A, Fische L. Long-term results of therapeutic local anesthesia (neural therapy) in 280 referred refractory chronic pain patients. BMC Complement Altern Med. 2015;15:200. https://doi.org/10.1186/s12906-015-0735-z.
3. Harris G. Neural Therapy and Its Role in the Effective Treatment of Chronic Pain. Practical Pain Management 2009;9(6). https://www.practicalpainmanagement.com/treatments/complementary/prolotherapy/neural-therapy-its-role-effective-treatment-chronicpain
4. Dosch, P. Dosch, M. Manual of Neural Therapy According to Huneke. New York, EUA: Thieme Medical Publishers; 2007.
5. Atalay NS, Sahin F, Atalay A, Akkaya N. Comparison of efficacy of neural therapy and physical therapy in chronic low back pain. Afr J Tradit Complement Altern Med. 2013;10(3):431-435. https://doi.org/10.4314/ajtcam.v10i3.8.
6. Weinschenk S, Hollmann MW, Göllner R, Picardi S, Strowitzki T, Diehl L, H, et al. Injections of Local Anesthetics into the Pharyngeal Region Reduce Trapezius Muscle Tenderness. Forsch Komplementmed. 2016;23(2):111-6. https://doi.org/10.1159/000444665.
7. Posadzki P, Alotaibi A, Ernst E. Adverse effects of homeopathy: a systematic review of published case reports and case series. Int J Clin Pract. 2012;66(12):1178-88. https://doi.org/10.1111/ijcp.12026.
8. Stub T, Kristoffersen AE, Alræk T, Musial F, Steinsbekk A. Risk in homeopathy: Classification of adverse events and homeopathic aggravations - A cross sectional study among Norwegian homeopath patients. Complement Ther Med. 2015;23(4):535-543.https://doi.org/10.1016/j.ctim.2015.06.004.
9. Stub T, Musial F, Kristoffersen AA, Alræk T, Liu J. Adverse effects of homeopathy, what do we know? A systematic review and metaanalysis of randomized controlled trials. Complement Ther Med. 2016;26:146-63. https://doi.org/10.1016/j.ctim.2016.03.013.
10. Šimurina T, Mraovic B, Župcic M, Graf Župcic S, Vulin M. Local anesthetics and steroids: contraindications and complications - clinical update. Acta Clin Croat. 2019;58(Suppl 1):53-61. https://doi.org/10.20471/acc.2019.58.s1.08.
11. Horde GW, Gupta V. Drug Clearance [Internet]. Treasure Island (FL): StatPearls Publishing; 2020. Disponible en: https://www.ncbi.nlm.nih.gov/books/NBK557758/.
12. Roman MJ, Pugh NL, Hendershot TP, Devereux RB, Dietz H, Holmes K, et al. Aortic Complications Associated With Pregnancy in Marfan Syndrome: The NHLBI National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions (GenTAC). Journal of the American Heart Association. J Am Heart Assoc. 2016;5(8):e004052. doi:10.1161/JAHA.116.004052.
13. Chou AS, Ma WG, Mok SC, Ziganshin BA, Peterss S, et al. Do familial aortic dissections tend to occur at the same age?. Ann Thorac Surg. 2017;103(2):546-550. doi: 10.1016/j.athoracsur.2016.06.007.
14. Nienaber CA, Rousseau H, Eggebrecht H, Kische S, Fattori R, et al. Randomized comparison of strategies for type B aortic dissection: The Investigation of stent grafts in aortic dissection (INSTEAD) trial. Circulation. 2009;120(25):2519-28. doi: 10.1161/CIRCULATIONAHA.109.886408.
15. Wang W, Wu J, Zhao X, You B, Li C. Type-A aortic dissection manifesting as acute inferior myocardial infarction: 2 case reports. Medicine (Baltimore). 2019;98(43):e17662. doi: 10.1097/MD.0000000000017662.