Chemotherapy in lymphoma and its close relation with human immunodeficiency virus /acquired immunodeficiency syndrome

Quimioterapia en linfoma y su estrecha relación con el virus de la inmunodeficiencia humana /síndrome de inmunodeficiencia adquirida

Human immunodeficiency virus (HIV) has been among global society for many years and cases have increased over time. Immunosuppression and acquired immunodeficiency syndrome (AIDS) greatly predispose to various diseases, such as lymphoma. Objective: to review chemotherapy in HIV/AIDS-related lymphoma, and the predisposition for further opportunistic infections Methods: a literature review in the PubMed and ScienceDirect databases, using descriptors: “lymphoma”, “neoplasms”, “chemotherapy”, “AIDS serodiagnosis” in English and Spanish, selecting 10 related articles. Conclusion: HIV-related immunosuppression poses high risk of developing varied neoplasms, especially lymphoma. Chemotherapy is the most effective treatment for these patients however, it exacerbates patients´ baseline condition, increasing susceptibility to opportunistic infections, which may worsen their situation, leading to consider chemotherapy as a risk factor.

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