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Mid ventricular takotsubo syndrome in the immediate postoperative period in a patient with an ectopic pregnancy

Síndrome de Takotsubo medio ventricular en postoperatorio inmediato de gestante con embarazo ectópico



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Kuratomi Nakamura, K., González García, A. M., Paredes Fernández, A. J. ., Mejía Cardona, A. F. ., Velásquez, P. A. ., & Tamayo Artunduaga, N. . (2023). Mid ventricular takotsubo syndrome in the immediate postoperative period in a patient with an ectopic pregnancy. Journal of Medicine and Surgery Repertoire. https://revistas.fucsalud.edu.co/index.php/repertorio/article/view/1409

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Kenyi Kuratomi Nakamura,

Residente de Medicina Interna. Universidad Libre Seccional Cali Colombia.


Angela María González García,

Residente de Ginecología y Obstetricia. Universidad Libre Seccional Cali.


Antonio José Paredes Fernández,

Residente de Medicina Interna. Universidad Libre Seccional Cali.


Andrés Felipe Mejía Cardona,

Residente de Medicina Interna. Universidad Libre Seccional Cali.


Introduction: Takotsubo cardiomyopathy (TCM) is characterized by acute and transient cardiac dysfunction, triggered by psychological or physical stressors. Although it is rare, TCM can present in 1-3% of patients consulting with acute coronary syndrome (ACS) manifestations. It has been described in pregnancy, especially in preeclampsia and in the postoperative period after cesarean delivery. We present an undescribed association in a young patient with an ectopic pregnancy in the immediate postoperative period. Case: 23-year-old woman, with no underlying comorbidities, who underwent surgery for an ectopic pregnancy. In the immediate postoperative period, she presented with sudden hemodynamic deterioration and cardiogenic shock. Severe left ventricular dysfunction with an ejection fraction of 17% and severe hypokinesis was documented after 48 hours of receiving norepinephrine and milrinone supportive therapy. Ventilatory and hemodynamic parameters improved after adding levosimendan and dobutamine. A control echocardiogram showed recovery of LVEF to 40% with a ventricular mid segment pattern. Takotsubo cardiomyopathy was considered. Cardiac MRI on day 9 after onset was normal showing full ventricular function recovery. Conclusion: Takotsubo cardiomyopathy may occur in young women of reproductive age exposed to surgical stress and may be induced by gestational conditions such as an ectopic pregnancy.


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  1. Templin C, Ghadri JR, Diekmann J, Napp LC, Bataiosu DR, Jaguszewski M, et al. Clinical Features and Outcomes of Takotsubo (Stress) Cardiomyopathy. N Engl J Med 2015;373(10):929-938. https://doi.org/10.1056/NEJMoa1406761.
  2. Napp LC, Bauersachs J. Takotsubo syndrome: between evidence, myths, and misunderstandings. Herz. 2020;45(3):252-266. https://doi.org/10.1007/s00059-020-04906-2.
  3. Khalid N, Ahmad SA, Shlofmitz E, et al. Pathophysiology of Takotsubo Syndrome [Internet]. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2022 [Updated 2022 Mar 9]. Disponible en: https://www.ncbi.nlm.nih.gov/books/NBK538160/
  4. Oh TK, Song I-A, Park Y, Hwang J-W, Jeon Y-T, Do S-H, et al. Prevalence and risk factors for postoperative stress-related cardiomyopathy in adults. PLoS One. 2017;12(12):e0190065. https://doi.org/10.1371/journal.pone.0190065.
  5. Medina de Chazal H, Del Buono MG, Keyser-Marcus L, Ma L, Moeller FG, Berrocal D, et al. Stress Cardiomyopathy Diagnosis and Treatment: JACC State-of-the-Art Review. J Am Coll Cardiol. 2018;72(16):1955-1971. https://doi.org/10.1016/j.jacc.2018.07.072.
  6. Lyon AR, Citro R, Schneider B, et al. Pathophysiology of Takotsubo Syndrome. J Am Coll Cardio. 2021;77(7):902–921. https://doi.org/10.1016/j.jacc.2020.10.060.
  7. Barmore W, Patel H, Harrell S, Garcia D, Calkins JB Jr. Takotsubo cardiomyopathy: A comprehensive review. World J Cardiol. 2022;14(6):355-362. https://doi.org/10.4330/wjc.v14.i6.355.
  8. Oindi FM, Sequeira E, Sequeira HR, Mutiso SK. Takotsubo cardiomyopathy in pregnancy: a case report and literature review. BMC Pregnancy Childbirth. 2019;19(1):89. https://doi.org/10.1186/s12884-019-2233-7.
  9. Yoshizawa M, Itoh T, Morino Y, Taniai S, Ishibashi Y, Komatsu T, et al. CIRC-8U study group. Gender Differences in the Circadian and Seasonal Variations in Patients with Takotsubo Syndrome: A Multicenter Registry at Eight University Hospitals in East Japan. Intern Med. 2021;60(17):2749-2755. https://doi.org/10.2169/internalmedicine.6910-20.
  10. Y-Hassan S, Per T. “Epidemiology, pathogenesis, and management of takotsubo syndrome.” Clin Auton Res. 2018;28(1):53-65. https://doi.org/10.1007/s10286-017-0465-z.
  11. Frangieh AH, Obeid S, Ghadri JR, Imori Y, D'Ascenzo F, Kovac M, Ruschitzka F, et al. InterTAK Collaborators. ECG Criteria to Differentiate Between Takotsubo (Stress) Cardiomyopathy and Myocardial Infarction. J Am Heart Assoc. 2016;5(6):e003418. https://doi.org/10.1161/JAHA.116.003418.
  12. Khan H, Gamble D, Mezincescu A, Abbas H, Rudd A, Dawson D. A systematic review of biomarkers in Takotsubo syndrome: A focus on better understanding the pathophysiology. Int J Cardiol Heart Vasc. 2021;34:100795. https://doi.org/10.1016/j.ijcha.2021.100795.
  13. Hong JY, Ryu SK, Park JY, Park SH, Choi J. Early Differentiation of Stress Cardiomyopathy from Acute Anterior Wall Myocardial Using Changing Cardiac Enzyme Patterns. J Cardiovasc Imaging. 2021;29(3):228-233. https://doi.org/10.4250/jcvi.2020.0167.
  14. Dagrenat C, Von Hunolstein JJ, Matsushita K, Thebaud L, Greciano S, Tuzin N, Meyer N, Trinh A, Jesel L, Ohlmann P, Morel O. Value of Cardiac Biomarkers in the Early Diagnosis of Takotsubo Syndrome. J Clin Med. 2020;9(9):2985. https://doi.org/10.3390/jcm9092985.
  15. Kinno R, Ono K. Takotsubo Syndrome: Optimizing Care with a Multidisciplinary Approach. J Multidiscip Healthc. 2021;14:2487-2499. https://doi.org/10.2147/JMDH.S283667.
  16. Gouvêa de Almeida Junior GL, Mansur Filho J, Albuquerque DC, Xavier SS, et al. Takotsubo Multicenter Registry (REMUTA) - Clinical Aspects, In-Hospital Outcomes, and Long-Term Mortality. Arq Bras Cardiol. 2020;115(2):207-216. https://doi.org/10.36660/abc.20190166.
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