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Tcell/Natural Killer Cell Nasal Type Lymphoma (NNKTL)
Linfoma nasal de células T/Natural Killer (LNT/NK)
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Case Reports
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Mora Hernández, O. E. ., González Payares, M. D. C., García Concha, A. M. ., Vargas Gualdron, L. V. ., Morales Naranjo, S. D. ., & Urquijo Pérez, P. A. . (2025). Tcell/Natural Killer Cell Nasal Type Lymphoma (NNKTL). Journal of Medicine and Surgery Repertoire, 34(3), 299-303. https://doi.org/10.31260/RepertMedCir.01217372.1489
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Oscar Eduardo Mora Hernández
Roles:
Maria Del Carmen González Payares
Roles:
Ana Maria García Concha
Roles:
Laura Vanessa Vargas Gualdron
Roles:
Samuel David Morales Naranjo
Roles:
Paola Andrea Urquijo Pérez
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Introduction: Tcell/natural killer cell nasal type lymphoma (NNKTL) is part of the post-thymic T-cell immunoproliferative lesions spectrum. It consists of a necrotic process that progressively destroys the nose, paranasal sinuses, palate, and other facial structures. Genetic factors have been described in its etiology. Diagnosis is based on clinical features supported by histopathological hematoxylin-eosin staining and immunohistochemistry. It is advisable to test for EBER (Epstein-Barr virus-encoded small RNAs) infection, for these two pathologies are associated. Treatment options vary depending on neoplasm classification. Clinical case: 58-year-old male patient who presented with a rapidly growing erythematous violaceous plaque on the nasal dorsum that evolved into an ulcer and destruction of the adjacent soft tissues. He was seen at the dermatology department, where taking a skin biopsy with a presumptive diagnosis of an extranodal NK cell/T cell lymphoma, nasal type, was considered. Conclusion: extranodal NK cell/T cell lymphoma, nasal type, is a rapidly progressive entity carrying significant organ involvement, hence early identification is of utmost importance to improve prognosis.
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