Atypical presentation of microscopic polyangiitis with renal, pulmonary, dermatological and central nervous system involvement

Presentación atípica de la poliangeítis microscópica con compomiso renal, pulmonar, dermatológico y del sistema nervioso central

Microscopic polyangiitis (MPA) is an autoimmune antineutrophil cytoplasmic antibody-associated (ANCA) small-vessel vasculitis. It is clinically characterized by glomerulonephritis and pulmonary capillaritis, however, skin, nerve and gastrointestinal tract involvement is also relatively common. A case is presented in a 17-year-old male patient with atypical manifestations, such as, pauci-immune glomerulonephritis, alveolar hemorrhage, cutaneous leukocytoclastic vasculitis and cerebral hemorrhage. MPA histologic and radiologic features were also reviewed.

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