Skip to main navigation menu Skip to main content Skip to site footer

A multi-factor approach to the physiopathology of obesity: COD2 model

Acercamiento multifactorial a la fisiopatología de la obesidad. Modelo de abordaje COD2 COD2 approach model




Section
Review Articles

How to Cite
Rosero Revelo, R., Palacio Uribe, J., Jaramillo, A. M., Polanco, J. P., Cubillos Rizo, P., Uribe Jaramillo, A., Cossio Salazar, I., Álzate Arbeláez, J. P., & Cendales, J. G. (2019). A multi-factor approach to the physiopathology of obesity: COD2 model: COD2 approach model. Journal of Medicine and Surgery Repertoire, 28(3), 145-151. https://doi.org/10.31260/RepertMedCir.v28.n3.2019.954

Dimensions
PlumX
license

   

Ricardo Rosero Revelo
    Jorge Palacio Uribe
      Adriana María Jaramillo
        Juan Pablo Polanco
          Paola Cubillos Rizo
            Alicia Uribe Jaramillo
              Isabel Cossio Salazar
                Juan Pablo Álzate Arbeláez
                  Juan Gabriel Cendales

                    Ricardo Rosero Revelo,

                    Médico Internista y Endocrinólogo COD2


                    Jorge Palacio Uribe,

                    Médico Deportólogo COD2


                    Adriana María Jaramillo,

                    Médica Pediatra y Endocrinóloga COD2


                    Paola Cubillos Rizo,

                    Médica Especialista en Naturopatía y Medicina Funcional COD2


                    Alicia Uribe Jaramillo,

                    Psicóloga Clínica y Maestría en Psicología


                    Obesity is currently considered as one of the major life-threatening conditions affecting the healthcare system. The accelerated increase in prevalence and mortality due to cardiovascular diseases establishes an historical precedent as a global public health issue. The increased incidence of obesity and chronic diseases, has led multiple health researchers to try to identify a clear triggering factor contributing to obesity. There are numerous causes which explain its aggressive, progressive and chronic behavior. However, they do not satisfactorily elucidate a unique triggering factor which would determine a unique treatment to help decelerate its rapid expansion. This article seeks to explain the major causal factors and mechanisms leading to obesity, in order to find the most appropriate approach for obese patients seeking treatment options (COD2 model).

                    Article visits 2739 | PDF visits 2071


                    Downloads

                    Download data is not yet available.
                    1. Popkin BM, Adair LS, Ng SW. Global nutrition transition and the pandemic of obesity in developing countries. Nutrition reviews. 2012;70(1):3-21. doi: 10.1111/j.1753-4887.2011.00456.x.
                    2. Hall KD, Guo J, Dore M, Chow CC. The progressive increase of food waste in America and its environmental impact. PloS one. 2009;4(11):e7940. doi: 10.1371/journal.pone.0007940.
                    3. Cordero P, Milagro F, Yoldi M, Campion J, Alfredo J, Hernández M, et al. Epigenética nutricional: una pieza clave en el rompecabezas de la obesidad. Rev Esp Obes. 2010;8(1):10-20.
                    4. Abondano J, Lizcano F. Epigenética en el origen de la obesidad: perspectiva desde la célula grasa. Revista Colombiana de Endocrinología, Diabetes & Metabolismo. 2017;4(4):24-31.
                    5. Joffe YT, Houghton CA. A Novel Approach to the Nutrigenetics and Nutrigenomics of Obesity and Weight Management. Current oncology reports. 2016;18(7):43. Epub 2016/05/25.
                    6. Dunford AR, Sangster JM. Maternal and paternal periconceptional nutrition as an indicator of offspring metabolic syndrome risk in later life through epigenetic imprinting: A systematic review. Diabetes & metabolic syndrome. 2017;11 Suppl 2:S655-S62. doi: 10.1016/j.dsx.2017.04.021.
                    7. Nielsen JH, Haase TN, Jaksch C, Nalla A, Sostrup B, Nalla AA, et al. Impact of fetal and neonatal environment on beta cell function and development of diabetes. Acta obstetricia et gynecologica Scandinavica. 2014;93(11):1109-22. doi: 10.1111/aogs.12504.
                    8. Block T, El-Osta A. Epigenetic programming, early life nutrition and the risk of metabolic disease. Atherosclerosis. 2017;266:31-40. doi: 10.1016/j.atherosclerosis.2017.09.003.
                    9. Hartwig FP, Loret de Mola C, Davies NM, Victora CG, Relton CL. Breastfeeding effects on DNA methylation in the offspring: A systematic literature review. PloS one. 2017;12(3):e0173070. doi: 10.1371/journal.pone.0173070
                    10. Dhasarathy A, Roemmich JN, Claycombe KJ. Influence of maternal obesity, diet and exercise on epigenetic regulation of adipocytes. Molecular aspects of medicine. 2017;54:37-49. doi: 10.1016/j.mam.2016.10.003
                    11. Braden A, Musher-Eizenman D, Watford T, Emley E. Eating when depressed, anxious, bored, or happy: Are emotional eating types associated with unique psychological and physical health correlates? Appetite. 2018;125:410-7. doi: 10.1016/j.appet.2018.02.022
                    12. Bourdier L, Orri M, Carre A, Gearhardt AN, Romo L, Dantzer C, et al. Are emotionally driven and addictive-like eating behaviors the missing links between psychological distress and greater body weight? Appetite. 2018;120:536-46. doi: 10.1016/j.appet.2017.10.013.
                    13. van Strien T. Causes of Emotional Eating and Matched Treatment of Obesity. Current diabetes reports. 2018;18(6):35. doi: 10.1007/s11892-018-1000-x.
                    14. Sainsbury K, Evans EH, Pedersen S, Marques MM, Teixeira PJ, Lahteenmaki L, et al. Attribution of weight regain to emotional reasons amongst European adults with overweight and obesity who regained weight following a weight loss attempt. Eating and weight disorders : EWD. 2019;24(2):351-61. doi: 10.1007/s40519-018-0487-0.
                    15. Ma J, Xiao L, Lv N, Rosas LG, Lewis MA, Goldhaber-Fiebert JD, et al. Profiles of sociodemographic, behavioral, clinical and psychosocial characteristics among primary care patients with comorbid obesity and depression. Preventive medicine reports. 2017;8:42-50. doi: 10.1016/j.pmedr.2017.07.010
                    16. Vittengl JR. Mediation of the bidirectional relations between obesity and depression among women. Psychiatry research. 2018;264:254-9. doi: 10.1016/j.psychres.2018.03.023.
                    17. Mauskopf SS, O'Leary AK, Banihashemi A, Weiner M, Cookston JT. Divorce and eating behaviors: a 5-day within-subject study of preadolescent obesity risk. Child Obes. 2015;11(2):122-9. doi: 10.1089/chi.2014.0053.
                    18. Ferrer RA, Green PA, Oh AY, Hennessy E, Dwyer LA. Emotion suppression, emotional eating, and eating behavior among parent-adolescent dyads. Emotion. 2017;17(7):1052-65. doi: 10.1037/emo0000295.
                    19. Matthews J, Huberty J, Leiferman J, Buman M. Psychosocial predictors of gestational weight gain and the role of mindfulness. Midwifery. 2018;56:86-93. doi: 10.1016/j.midw.2017.10.008.
                    20. World Health Organization. Obesity and overweight [Internet]. World Health Organization; 2018 [citado 2018 junio 1]; Disponible en: https://www.who.int/news-room/fact-sheets/detail/obesity-and-overweight.
                    21. World Health Organization. Global and regional food consumption patterns and trends [Internet]. World Health Organization; 2008 [citado 2018 junio 1]; Disponible en: https://www.who.int/nutrition/topics/3_foodconsumption/en/.
                    22. Roser M, Ritchie H. Our World in Data [Internet]. World in Data; 2019 [citado 2018 junio 1]; Disponible en: https://ourworldindata.org/food-per-person.
                    23. Rouhani MH, Haghighatdoost F, Surkan PJ, Azadbakht L. Associations between dietary energy density and obesity: A systematic review and meta-analysis of observational studies. Nutrition. 2016;32(10):1037-47. doi: 10.1016/j.nut.2016.03.017.
                    24. Asghari G, Mirmiran P, Yuzbashian E, Azizi F. A systematic review of diet quality indices in relation to obesity. The British journal of nutrition. 2017;117(8):1055-65. doi: 10.1017/S0007114517000915.
                    25. Medina-Remon A, Kirwan R, Lamuela-Raventos RM, Estruch R. Dietary patterns and the risk of obesity, type 2 diabetes mellitus, cardiovascular diseases, asthma, and neurodegenerative diseases. Critical reviews in food science and nutrition. 2018;58(2):262-96. doi: 10.1080/10408398.2016.1158690
                    26. Fogelholm M, Anderssen S, Gunnarsdottir I, Lahti-Koski M. Dietary macronutrients and food consumption as determinants of long-term weight change in adult populations: a systematic literature review. Food & nutrition research. 2012;56. doi: 10.3402/fnr.v56i0.19103
                    27. Rouhani MH, Salehi-Abargouei A, Surkan PJ, Azadbakht L. Is there a relationship between red or processed meat intake and obesity? A systematic review and meta-analysis of observational studies. Obesity reviews : an official journal of the International Association for the Study of Obesity. 2014;15(9):740-8. doi: 10.1111/obr.12172.
                    28. Hauner H, Bechthold A, Boeing H, Bronstrup A, Buyken A, Leschik-Bonnet E, et al. Evidence-based guideline of the German Nutrition Society: carbohydrate intake and prevention of nutrition-related diseases. Annals of nutrition & metabolism. 2012;60 Suppl 1:1-58. doi: 10.1159/000335326.
                    29. Mozaffarian D, Hao T, Rimm EB, Willett WC, Hu FB. Changes in diet and lifestyle and long-term weight gain in women and men. The New England journal of medicine. 2011;364(25):2392-404. doi: 10.1056/NEJMoa10142
                    30. Juul F, Hemmingsson E. Trends in consumption of ultra-processed foods and obesity in Sweden between 1960 and 2010. Public health nutrition. 2015;18(17):3096-107. doi: 10.1017/S1368980015000506
                    31. Costa CS, Del-Ponte B, Assuncao MCF, Santos IS. Consumption of ultra-processed foods and body fat during childhood and adolescence: a systematic review. Public health nutrition. 2018;21(1):148-59. doi: 10.1017/S1368980017001331.
                    32. Keller A, Bucher Della Torre S. Sugar-Sweetened Beverages and Obesity among Children and Adolescents: A Review of Systematic Literature Reviews. Child Obes. 2015;11(4):338-46. doi: 10.1089/chi.2014.0117.
                    33. Nogueira Bezerra I, de Carvalho Gurgel AO, Bastos Barbosa RG, Bezerra da Silva Junior G. Dietary Behaviors among Young and Older Adults in Brazil. The journal of nutrition, health & aging. 2018;22(5):575-80. doi: 10.1007/s12603-017-0978-0.
                    34. Darmon N, Drewnowski A. Contribution of food prices and diet cost to socioeconomic disparities in diet quality and health: a systematic review and analysis. Nutrition reviews. 2015;73(10):643-60. doi: 10.1093/nutrit/nuv027.
                    35. Pitt E, Gallegos D, Comans T, Cameron C, Thornton L. Exploring the influence of local food environments on food behaviours: a systematic review of qualitative literature. Public health nutrition. 2017;20(13):2393-405. doi: 10.1017/S1368980017001069.
                    36. Boyland EJ, Nolan S, Kelly B, Tudur-Smith C, Jones A, Halford JC, et al. Advertising as a cue to consume: a systematic review and meta-analysis of the effects of acute exposure to unhealthy food and nonalcoholic beverage advertising on intake in children and adults. The American journal of clinical nutrition. 2016;103(2):519-33. doi: 10.3945/ajcn.115.120022.
                    37. Davenport L. Junk Food Ads Increase Teenage Calorie Consumption [Internet]. Medscape; 2018 [citado 2018 junio 1]; Disponible en: https://www.medscape.com/viewarticle/897317.
                    38. Organización Mundial de la Salud. Actividad física y salud [Internet]. Organización Mundial de la Salud; 2018 [citado 2018 febrero]; Disponible en: https://www.who.int/dietphysicalactivity/pa/es/.
                    39. Ministerio de Salud y Protección Social. Encuesta nacional de la situación nutricional en Colombia ENSIN-2015 [Internet]. Colombia: Ministerio de Salud y Protección Social; [citado 2018 junio]; Disponible en: https://www.minsalud.gov.co/salud/publica/epidemiologia/Paginas/encuesta-nacional-de-situacion-nutricional-ensin.aspx.
                    40. Cederholm T, Morley JE. Sarcopenia: the new definitions. Current opinion in clinical nutrition and metabolic care. 2015;18(1):1-4. doi: 10.1097/MCO.0000000000000119
                    41. Barber TM. Is obesity a disease? Expert review of endocrinology & metabolism. 2018;13(2):59-61. doi: 10.1080/17446651.2018.1427580.
                    42. Pedersen BK. Anti-inflammatory effects of exercise: role in diabetes and cardiovascular disease. European journal of clinical investigation. 2017;47(8):600-11. doi: 10.1111/eci.12781.
                    43. Bowden Davies KA, Sprung VS, Norman JA, Thompson A, Mitchell KL, Halford JCG, et al. Short-term decreased physical activity with increased sedentary behaviour causes metabolic derangements and altered body composition: effects in individuals with and without a first-degree relative with type 2 diabetes. Diabetologia. 2018;61(6):1282-94. doi: 10.1007/s00125-018-4603-5.
                    44. Hoffmann C, Weigert C. Skeletal Muscle as an Endocrine Organ: The Role of Myokines in Exercise Adaptations. Cold Spring Harbor perspectives in medicine. 2017;7(11). doi: 10.1101/cshperspect.a029793.
                    45. Poirier P, Giles TD, Bray GA, Hong Y, Stern JS, Pi-Sunyer FX, et al. Obesity and cardiovascular disease: pathophysiology, evaluation, and effect of weight loss: an update of the 1997 American Heart Association Scientific Statement on Obesity and Heart Disease from the Obesity Committee of the Council on Nutrition, Physical Activity, and Metabolism. Circulation. 2006;113(6):898-918. doi: 10.1161/CIRCULATIONAHA.106.171016
                    46. Bays HE, Gonzalez-Campoy JM, Bray GA, Kitabchi AE, Bergman DA, Schorr AB, et al. Pathogenic potential of adipose tissue and metabolic consequences of adipocyte hypertrophy and increased visceral adiposity. Expert review of cardiovascular therapy. 2008;6(3):343-68. doi: 10.1586/14779072.6.3.343.
                    47. Bays HE. Adiposopathy: Is “Sick Fat” a Cardiovascular Disease? Journal of the American College of Cardiology. 2011;57(25):2461-73. doi: 10.1016/j.jacc.2011.02.038
                    48. Bay H, Ballantyne C. Adiposopathy: why do adiposity and obesity cause metabolic disease? . Future Lipidol. 2006;1(4):389-420.
                    49. Bays HE, Gonzalez-Campoy JM, Henry RR, Bergman DA, Kitabchi AE, Schorr AB, et al. Is adiposopathy (sick fat) an endocrine disease? International journal of clinical practice. 2008;62(10):1474-83. doi: 10.1111/j.1742-1241.2008.01848.x
                    Sistema OJS 3.4.0.5 - Metabiblioteca |