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The unsolved scientific questions, the complexity of the practice of medicine, the new information and the inevitable differences of opinion, stimulated me to write this article with the purpose of providing relevant and defensible updated recommendations for the prevention and treatment of infections. in the newborn (RN), who with his immaturity and in a new environment is susceptible to the invasion and rapid spread of germs, so that sepsis, with or without meningitis, occurs in a much more remarkable way than in no other period of life.
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