Nephropathy and globular dysmorphism in urinary sediment

Nefropatía y dismorfismo globular en sedimiento urinario

The objective of this research is to describe the importance of the quantification of globular dysmorphism in the urinary sediment of patients with a histological study of renal biopsy, as a diagnostic aid for nephropathies, as well as to determine the frequency of these alterations and to compare the findings of the sediment. urinary with the biopsy. The samples were obtained from ten patients over 18 years of age who attended the renal unit of the Hospital of San José, and who underwent quantification of dysmorphism before the biopsy. Of the ten patients analyzed, two had globular dysmorphism less than 50%, six between 51 and 80% and in two it was greater than 81%. It was observed that there may be a relationship between globular dysmorphism in urinary sediment and nephropathies, however, studies and better structured diagnostic tests are required, in order to expand the knowledge acquired on this subject.

Birch D F, Fairley K F, Whitworth J A, et al Urinary erythrocyte morphology in the diagnosis of glomerular hematuria. Clinic Nephrology, 1983; 20: 78-84.

Chang Bs. Red cell morphologyas a diagnostic aid in hematuria. JAMA 1984; 252: 1747-49.

Fairley KF, Birch DF. Hematuria simple method for identifying glomerular bleeding. Kidney Int 1982; 21: 105-8.

Rosemberg H. Anatomía patológica del aparato urinario genital masculino. (Citado 2004 noviembre 21) disponible en www.escuela.med.puc.cl.

Stephan R, Eckhad R. Rathert P.Microscopic hematuria: advances in identification of glomerular dysmorphic erytrocytes. J. Urology 1991; 146: 680-84.

Torres A, Sellares V. Manual de Nefrología. Madrid: Manual Moderno Harcourtk, 1998, p.3.

Villanueva V. Enfoque diagnóstico de hematuria. (Citado 2001 feb) Disponible en www.escuela.med.puc.cl.