Incidental adenocarcinoma of prostate in transurethral resection: Amount of material processed

Adenocarcinoma incidental de próstata en resección transuretral: Cantidad de material procesado

The performance of transurethral prostate resections is very common as a therapeutic procedure for benign obstructive urinary pathologies of prostate origin. The study of the obtained material seeks first to rule out the presence of a prostate adenocarcinoma that has gone unnoticed in the pre-surgical studies of the patient. However, there is no clarity regarding the amount of the sample that must be processed to obtain a diagnosis in all cases of Tlb stage prostate adenocarcinoma and a high percentage of the Tla stage. This study gathers 112 cases of TUR in which all the tissue obtained was processed, describing the demographic variables, weight of the specimen, number of blocks, consecutive of the positive blocks and stage of the disease. It was found that patients in Tlb stage are younger than Tla. There is no difference in the detection frequency of prostatic adenocarcinoma among all the studied processing modalities (four and eight first blocks). It is recommended to analyze a larger sample of cases to obtain data that allow us to establish an ideal cutoff point. Abbreviations: CIP, incidental carcinoma of the prostate; RTU, transurethral resection of the prostate.

1. Epstein J. The prostate and seminal vesicles. En: Milis S., Carter D, Reuter V., Greenson J., Stoler M., editors. Sternberg's diagnostic surgical pathology. 4th Edition. Philadelphia: Lippincott Williams & Wilkins; 2004. p: 2083 — 2132.

2. Young R., Srigley J., Amin M., Ulbright T., Cubilla A., Editors. Atlas of tumor pathology. Tumors of the prostate gland, seminal vesicles, male urethra and penis. 3rd series. Fascicle 28. Washington, DC: Armed Forces Institute of Pathology.

3. Coley CM, Barry MJ, Fleming C, Fahs MC, Mulley AG. Early detection of prostate cancel.. Part I: Prior probability and effectiveness of test. American College of Physicians. Ann Intern Med. 1997 Mar 15;126(6):394-406.

4. Eble J.N., Sauter G., Epstein J., Sesterhenn I., Editors. World Health Organization Classification of tumors. Pathology and genetics of Tumors of the Urinary System and Male Genital Organs. Lyon: IARC Press; 2005.

5. Rohr LR. Incidental adenocarcinoma in transurethral resections of the prostate. Partial versus complete microscopic examination. Am J Surg Pathol. 1987 Jan;11(1):53-8.

6. Humphrey P., Walther P., Adenocarcinoma of the prostate. I. Tissue Sampling Considerations. American Journal of Clinical Pathology. 1993. Jun; 99(6): 746 — 759.

7. Rosai J. Editor. Rosai and Ackerman's Surgical Pathology. 9th Edition. London: Mosby; 2004.

8. Humphrey P., Walther P., Adenocarcinoma of the prostate. I. Tissue Sampling Considerations. American Journal of Clinical Pathology. 1993. Jun; 99(6): 746 — 759.

9. Lester C. S., editor. Manual of surgical pathology. Philadelphia: Lippincott Williams & Wilkins: 2001.

10. Hruban R., Westra W., Phelps T., Isacson C., editors. Surgical Pathology Dissection. An Illustrated Guide. New York: Springer. 2003.

11. Murphy WM, Dean PJ, Brasfield JA, Tatum L. Incidental carcinoma of the prostate: how much sampling is adequate? Am J Surg Pathol 1986; 10:170-4.

12.Newman AJ Jr, Graham MA, Carlton CE Jr, Lieman S. Incidental carcinoma of the prostate at the time of transurethral resection: importance of evaluating every chip. J Urol. 1982 Nov;128(5):948-50.

13. McDowell PR, Fox WM, Epstein JI. Is submission of remaining tissue necessary when incidental carcinoma of the prostate is found on transurethral resection? Hum Pathol. 1994 May;25(5):493-7.