Epilepsy: New classification (ILAE 2001). Comparative study with the ILAE 1981 and 1989

Epilepsia: Nueva clasificación (ILAE 2001). Estudio comparativo con la ILAE 1981 y 1989

The International League Against Epilepsy proposed a new classification of epilepsy in 2001, supported by five axes that reflect the findings so far known. The results of its application are reported in patients who come to the neurology clinic of the Hospital of San José de Bogotá D.C. It is a prospective descriptive observational study. A total of 95 cases were included, observing the highest frequency of presentation of the first seizure in the range of 10 to 20 years, of which 98.9% presented with active epilepsy. The coincidence between ictal semiology (axis 1) and type of crisis (axis 2) was 87.4%. The epileptic syndrome (axis 3) was partial in 31.6% and generalized in 64.2% of the cases. The most identified etiology (axis 4) corresponded to chromosomal abnormalities in 29.5% and was not recognized in 41.1%. When evaluating the degree of affectation of the subject (axis 5) with the QOLIE-31 questionnaire, its application allowed to quantify the quality of life and we considered that its use would allow to optimize the management of the patients. In general, the majority could be categorized with this classification proposal in a similar way to when the previous two classifications ILAE 1981 and 1989 were applied. Abbreviations: ILAE, international league against epilepsy.

1. Pradilla G, Boris E, Vesga A. Estudio neuroepidemiológico nacional (EPINEURO) colombiano. Rev Panam Salud Pública. 2003; 14(2): 104-10.

2. Commision on Classification and Terminology of the Internacional League Against Epilepsy. Proposal for revised clinical and electroencephalographic classification of epileptic seizures. Epilepsia. 1981; 22(4): 489-501.

3. Commission on Classification and Terminology of the International League Against Epilepsy. Proposal for revised classification of epilepsies and epileptic syndromes. Epilepsia 1989; 30(4) 389-99.

4. Engel J Jr. A proposed diagnostic scheme for people with epileptic seizures and with epilepsy: report of de ILAE task force on classification and terminology. Epilepsia 2001; 42(6): 796-803.

5. Vickrey BG, Perrine KR, Hays RD. et al. Quality of life in epilepsy QOLIE-31 (version 1.0); scoring manual and patient inventory, Santa Mónica, CA: RAND, 1993.

6. Cramer JA, Perrine K, Devinsky O, Bryant-Comstock L, Meador K, Hermann B. Development and Cross- Cultural Traslations of a 31-Item Quality of Life in Epilepsy Inventory. Epilepsia. 1998; 31(1): 81-8.

7. Eslava-Cobos J, Nariño D. Experience with the International League Against Epilepsy proposals for classification of epileptic seizures and the epilepsies and epileptic syndromes in a pediatric outpatient epilepsy clinic. Epilepsia. 1989; 30(1): 112-15.

8. Nieto-Barrera M. Reflexiones sobre la clasificación internacional de epilepsias y síndromes epilépticos y el esquema diagnóstico propuesto por un grupo de trabajo de la ILAE. Rev Neurol. 2002; 34 (6): 537-43.

9. Rey-Becerra A, Díaz-Marcaccio R, Castro Fernández M, Scavone-Mauro C, Ruggia-Aritzti R. Aplicación de la clasificación de la International League Against Epilepsy. Estudio retrospectivo en un hospital uruguayo. Rev Neurol 2005; 41 (6): 331-7.