Epithelial carcinomas of the ovary of high and low grade: State of Art

Carcinomas epiteliales del ovario de alto y bajo grado: Estado de Arte

Ovarian epithelial cancer in Colombia is the second cause of morbidity and mortality due to gynecological tumors after carcinoma of the cervix. It usually presents in advanced stages and survival is poor. Recent studies of clinical and molecular types have revealed new theories about carcinogenesis, proposing a dual model with tumors types I and II. This article seeks to expand and update the information on these new theories and deepen histopathological and molecular knowledge. For the review of the literature, a search strategy was structured using the terms ovarian carcinoma, tumors type I-II, KRAS, BRAF, p-53 (MeSH and not Mesh), which were articulated with Boolean operators in the following bases of data: pubmed, ebscohost, base, filtering the results by review articles.

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