Gastrointestinal bleeding in hospitalized patients

Sangrado gastrointestinal en pacientes hospitalizados

Gastrointestinal bleeding is a potential complication of the patient who is hospitalized. As early descriptions in intensive care related bleeding from stress ulcers with high mortality, the investigation was increasing in critically ill patients. The same did not happen with the hospitalized and the available jobs are scarce. The main risk factors have been described in the critics (mechanical ventilation more than 48 hours and coagulopathy). The effectiveness of the therapy has not been demonstrated in those in the general ward. Indirect evidence shows marginal utility of these drugs in the prevention of gastrointestinal bleeding. In critical cases there is abundant information but the interpretation is confusing. A high formulation rate has been documented to prevent bleeding in hospitalized patients, most without clear indication, which can expose the patient to unnecessary adverse events and additional costs to the health system. Strategies are recommended to implement guidelines for the rational use of these drugs. Abbreviations: SGI, gastrointestinal bleeding; SRMD, stress-related mucosal disease; NSAIDs, non-steroidal anti-inflammatories; ASHP, American Society of Health-System Pharmacists; FDA, Food and Drug Administration; GERD, gastroesophageal reflux disease.

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