Post operative period of transnasal endoscopic surgery for polyposis: use of Montelukast and relapse follow up
Posoperatorio endoscópico transnasal por poliposis: uso de Montelukast y seguimiento a la recurrencia
Show authors biography
Nasal polyposis is one of the most common reasons for consultation in rhinosinusology with an insidious presentation with high impact on quality of life and poor response to common treatments. Objective: to describe relapse of nasal polyposis and level of control with the use of montelukast in the postoperative period of transnasal endoscopic surgery at Hospital de San José, Bogotá DC. Methods: preliminary report on a cohort prospective study with a 6-month follow up of 12 patients operated for nasal polyposis, using a 10 mg daily dose of montelukast. Results: a satisfactory symptomatic control was obtained with montelukast combined with topic steroids during the postoperative period in morethan 75% of patients. Adherence to treatment was adequate in more than 90% of cases. Early relapses (between second and third month) were found by nasofibro-laryngoscopy in 33% of 12 patients after a 6-month follow-up. Conclusion: the use of montelukast is acknowledged as a factor which combined with the classical treatment with nasal topic steroids, achieves adequate symptomatic control and is promissory for relapse prevention.
Article visits 233 | PDF visits 399
Downloads
1. Pawliczak R, Lewandowska-Polak A, Kowalski ML. Pathogenesis ofnasal polyps: an update. Curr Allergy Asthma Rep. 2005;5:463-7 J.
2. Nasal polyps: origin, etiology, pathogenesis, and structure. In: Kennedy D, Bolger W. Diseases of the sinuses diagnosis and management. Hamilton : B.C. Decker; 2001.
3. Chiu AG, Kennedy DW. Surgical management ofchronic rhinosinusitis and nasal polyposis: a review of the evidence. Curr Allergy Asthma Rep. 2004;4:486-489.
4. Lund VJ, Kennedy DW. Staging for rhinosinusitis. Otolaryngol HeadNeck Surg. 1997;117:S35-S40.
5. Llorente JL, Martinez-Farreras A, Rodrigo JP et al. [Nasal polyposis: postoperative long term results (5 years) after endoscopic sinus surgery]. Acta Otorrinolaringol Esp. 2002;53: 102-9.
6. Wynn R, Har El G. Recurrence rates after endoscopic sinus surgery for massive sinus polyposis. La1yngoscope. 2004;114:811-13.
7. Haberal I, CoreyJP. The role of leukotrienes in nasal allergy. Otolaryngol HeadNeckSurg. 2003;129:274-79.
8. Kirtsreesakul V. Update on nasal polyps: etiopathogenesis. J Med Assoc Thai. 2005;88:1966-72.
9. KJemi PJ, Virolainen E, Puhakka H. Theeffectofintranasal beclomethasone dipropionate on the nasal mucosa. Rhinology. 1980;18: 19-24.
10. Blumstein GI, Tuft L. Allergy treatment in recurren! nasal polyposis: its importance and value. Am JMedSci. 1957;234: 269-80.
11. Jantti-Alanko S, Holopainen E, Malmberg H. Recurrence of nasal polyps after surgical treatment. Rhinol Suppl. l 989;8:59-64.:59-64.
12. Wigand ME, Hosemann W. Microsurgical treatrnent of recurrent nasal polyposis. Rhinol Suppl. l 989;8:25-9.
13. Friedman WH, Katsantonis GP. Intranasal and transantral ethmoidectomy: a 20-yearexperience. Laryngoscope. 1990;100:343-48.
14. Patriarca G, Bellioni P, Nucera E et al. Intranasal treatment with lysine acetylsalicylate in patients with nasal polyposis. Ann Allergy. 1991;67:588-92.