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Gestational diabetes affects 2-15 percent of pregnancies. Risk factors include obesity, impaired glucose tolerance, family history revealing diabetes mellitus and antecedents of a previous pregnancy resulting in fetal death. Diagnosis is based on two abnormal values in the oral glucose tolerance test. Medical management is based on a hypocaloric diet and exercise. Pharmacologic therapy with insulin has been traditional. The use of fast onset insulin analogues was approved in 1996. Follow-up and metabolic control, as well as relapses of gestational diabetes and the development of type 2 diabetes mellitus are herein analyzed.
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