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Kleine-Levin syndrome is a rare disorder characterized by sleep pattern alterations and psychiatric symptoms which may be precipitated by various factors, among which are infections and trauma. The most common symptoms are: hypersomnia, cognitive alterations (including a specific derealization sensation), eating disorders, hypersexuality, compulsions and depression. We present the case of a 16-year old male patient, in whom disease progression and cyclical episodes were the clue to diagnosing this syndrome. We also review differential diagnosis, existing trials, and disease diagnosis and management.
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