Meniere's disease: Treatment with intratympanic corticosteroid. Clinical evolution
Enfermedad de meniére: Tratamiento con corticoide intratimpánico. Evolución Clínica
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Mora Vera, A., Fernández Padilla, M., & Peña Torres, E. (2008). Meniere’s disease: Treatment with intratympanic corticosteroid. Clinical evolution. Journal of Medicine and Surgery Repertoire, 17(4), 191–198. https://doi.org/10.31260/RepertMedCir.v17.n4.2008.517
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Research Article
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Abstract
Objective: to describe the experience with the use of intratympanic corticosteroids for the treatment of Meniere's disease, at the Hospital de San José. Study: descriptive observational type of case series. Methods: patients with Meniere's disease according to the criteria established by the American Academy of Otolaryngology (AA OHNS) in 1995, who were studied the audiometric changes and symptom improvement after the application of CIT. Two patients improved their audiometry, one of them with profound hearing loss recovered to moderate and another one improved according to the AA OHNS criteria. Conclusion: Intratympanic therapy with dexamethasone may be useful in the treatment of Meniere's disease to control the symptoms and auditory deterioration. In our study no complications related to the procedure were found. Abbreviations: MS, Meniere's disease; CIT, intratympanic corticoid.
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References
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• Boles R, Rice DH, Hybels R, Work WP. Conservative management of Méniére's disease: Furstenberg regimen revisited. Ann Otol Rhinol Laryngol. 1975 Jul-Aug;84(4 Pt 1):513-7.
• Committee on Hearing and Equilibrium guidelines for the diagnosis and evaluation of therapy in Meniére's disease. American Academy of Otolaryngology-Head and Neck Foundation, Inc. Otolaryngol Head Neck Surg. 1995 Sep;113(3):181-5.
• Chandrasekhar SS, Rubinstein RY, Kwartler JA, Gatz M, Connelly PE, Huang E, Baredes S. Dexamethasone pharmacokinetics in the inner ear: comparison of route of administration and use of facilitating agents. Otolaryngol Head Neck Surg. 2000 Apr;122(4):521-8.
• Choung YH, Park K, Shin YR, Cho MJ. Intratympanic dexamethasone injection for refractory sudden sensorineural hearing loss. Laryngoscope. 2006 May;116(5):747-52.
• Doyle KJ, Bauch C, Battista R, Beatty C, Hughes GB, Ma son J, Maw J, Musiek FL. Intratympanic steroid treatment: a review. Otol Neurotol. 2004 Nov;25(6): 1034-9.
• García-Purriños FJ, Ferri E, Rosell A, Calvo J. [Combined intratympanic and intravenous dexomethasone to control vertigo in Meniere disease] Acta Otorrinolaringol Esp. 2005 Feb;56(2):74-7.
• Hillman TM, Arriaga MA, Chen DA. Intratympanic steroids: do they acutely improve hearing in cases of cochlear hydrops?. Laryngoscope. 2003 Nov;113(11):1903-7.
• Jackson CG, Glasscock ME 3rd, Davis WE, Hughes GB, Sismanis A. Medical management of Meniére's disease. Ann Otol Rhinol Laryngol. 1981 Mar-Apr;90(2 Pt 1):142-7.
• Parnes LS, Sun AH, Freeman DJ. Corticosteroid pharmacokinetics in the inner ear fluids: an animal study followed by clinical application. Laryngoscope. 1999 Jul;109(7 Pt 2):1-17.
• Patogenia de la enfermedad de Meniére: consideraciones terapéuticas. Clin Otorrinolaringol Norte America. 2002;3 :iii-659.
• Pérez Fernández N, Pérez Garrigues H, Antolí Candela F, García Ibáñez E. [Meniére's disease: diagnostic criteria, criteria to establish stages, and standards for treatment evaluation. Bibliographic review and update] Acta Otorrinolaringol Esp. 2002 Nov;53(9):621-6.
• Ruckenstein MJ. Autoimmune inner ear disease. Curr Opin Otolaryngol Head Neck Surg. 2004 Oct;12(5):426-30.
• Sennaroglu L, Sennaroglu G, Gursel B, Dini FM. Intratympanic dexamethasone, intratympanic gentamicin, and endolymphatic sac surgery for intractable vertigo in Meniere's disease. Otolaryngol Head Neck Surg. 2001 Nov;125(5):537-43.
• Silverstein H, Isaacson JE, Olds MJ, Rowan PT, Rosenberg S. Dexamethasone inner ear perfusion for the treatment of Meniere's disease: a prospective, randomized, doubleblind, crossover trial. Am J Otol. 1998 Mar;19(2):196- 201.
• Xenellis J, Papadimitriou N, Nikolopoulos T, Maragoudakis P, Segas J, Tzagaroulakis A, Ferekidis E. Intratympanic steroid treatment in idiopathic sudden sensorineural hearing loss: a control study. Otolaryngol Head Neck Surg. 2006 Jun;134(6):940-5.
• Boles R, Rice DH, Hybels R, Work WP. Conservative management of Méniére's disease: Furstenberg regimen revisited. Ann Otol Rhinol Laryngol. 1975 Jul-Aug;84(4 Pt 1):513-7.
• Committee on Hearing and Equilibrium guidelines for the diagnosis and evaluation of therapy in Meniére's disease. American Academy of Otolaryngology-Head and Neck Foundation, Inc. Otolaryngol Head Neck Surg. 1995 Sep;113(3):181-5.
• Chandrasekhar SS, Rubinstein RY, Kwartler JA, Gatz M, Connelly PE, Huang E, Baredes S. Dexamethasone pharmacokinetics in the inner ear: comparison of route of administration and use of facilitating agents. Otolaryngol Head Neck Surg. 2000 Apr;122(4):521-8.
• Choung YH, Park K, Shin YR, Cho MJ. Intratympanic dexamethasone injection for refractory sudden sensorineural hearing loss. Laryngoscope. 2006 May;116(5):747-52.
• Doyle KJ, Bauch C, Battista R, Beatty C, Hughes GB, Ma son J, Maw J, Musiek FL. Intratympanic steroid treatment: a review. Otol Neurotol. 2004 Nov;25(6): 1034-9.
• García-Purriños FJ, Ferri E, Rosell A, Calvo J. [Combined intratympanic and intravenous dexomethasone to control vertigo in Meniere disease] Acta Otorrinolaringol Esp. 2005 Feb;56(2):74-7.
• Hillman TM, Arriaga MA, Chen DA. Intratympanic steroids: do they acutely improve hearing in cases of cochlear hydrops?. Laryngoscope. 2003 Nov;113(11):1903-7.
• Jackson CG, Glasscock ME 3rd, Davis WE, Hughes GB, Sismanis A. Medical management of Meniére's disease. Ann Otol Rhinol Laryngol. 1981 Mar-Apr;90(2 Pt 1):142-7.
• Parnes LS, Sun AH, Freeman DJ. Corticosteroid pharmacokinetics in the inner ear fluids: an animal study followed by clinical application. Laryngoscope. 1999 Jul;109(7 Pt 2):1-17.
• Patogenia de la enfermedad de Meniére: consideraciones terapéuticas. Clin Otorrinolaringol Norte America. 2002;3 :iii-659.
• Pérez Fernández N, Pérez Garrigues H, Antolí Candela F, García Ibáñez E. [Meniére's disease: diagnostic criteria, criteria to establish stages, and standards for treatment evaluation. Bibliographic review and update] Acta Otorrinolaringol Esp. 2002 Nov;53(9):621-6.
• Ruckenstein MJ. Autoimmune inner ear disease. Curr Opin Otolaryngol Head Neck Surg. 2004 Oct;12(5):426-30.
• Sennaroglu L, Sennaroglu G, Gursel B, Dini FM. Intratympanic dexamethasone, intratympanic gentamicin, and endolymphatic sac surgery for intractable vertigo in Meniere's disease. Otolaryngol Head Neck Surg. 2001 Nov;125(5):537-43.
• Silverstein H, Isaacson JE, Olds MJ, Rowan PT, Rosenberg S. Dexamethasone inner ear perfusion for the treatment of Meniere's disease: a prospective, randomized, doubleblind, crossover trial. Am J Otol. 1998 Mar;19(2):196- 201.
• Xenellis J, Papadimitriou N, Nikolopoulos T, Maragoudakis P, Segas J, Tzagaroulakis A, Ferekidis E. Intratympanic steroid treatment in idiopathic sudden sensorineural hearing loss: a control study. Otolaryngol Head Neck Surg. 2006 Jun;134(6):940-5.