Current management of cervical microinvasive cancer: Hospital de San José Manejo actual del cáncer microinvasor del cérvis: Hospital de San José

Abstract

In the world, cervical cancer ranks second in incidence after breast cancer and about three quarters of cases occur in developing countries. During the last two decades the incidence in the United States has decreased by almost a third thanks to the advent and application of screening programs. The association between cervical cancer and a causative agent transmitted in the sexual relationship called human papillomavirus has been established for a long time, which in the pathogenesis has a prevalence of HPV DNA in more than 90% of preinvasive lesions. invaders Cervical carcinoma is diagnosed in 21% of young women with active sexual life and who have not yet completed their desire for parity. This article reviews the current strategies in the management of patients with microinvasive carcinoma of the cervix and considers the mechanisms of therapeutic action. Abbreviations: HPV, human papillomavirus; NIC, intracervical neoplasia; LIE, intraepithelial lesion.