Care of the newborn with persistent pulmonary hypertension

Atención al recién nacido con hipertensión pulmonar persistente

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Diana Arias
Claudia Narváez

Abstract

Persistent pulmonary hypertension syndrome of the newborn is a clinical condition that occurs in the presence of some risk factors, conditioned by persistent high pressure in the pulmonary artery that alters the transition from foetal to neonatal circulation.
Objective: To create a clinical practice guideline for managing these patients.
Methodology: The principles defined by the Colombian Ministry of Social Protection in its instructions to develop evidence-based clinical practice guidelines were followed.
Materials and methods: A search was made in the literature using Lilacs, Embase, PubMed, Mdconsult, Cochrane, Scopus, Clinicaltrials.gov databases and internet browsers, in English and Spanish.
Discussion: This syndrome occurs in 1.9 per 1000 of live births, and its incidence is estimated at 0.2% of all live-born infants. It is considered an important problem in our neonatal intensive care unit (NICU) as it contributes to morbidity and mortality in preterm or term infants. It is not a singular disease, and may be primary or secondary. An analysis is also presented of the conditions that account for the main reasons for admission to the NICU such as in-utero and perinatal asphyxia, infection, meconium aspiration syndrome, respiratory distress syndrome, and hypoplastic lungs.
Conclusions: Early diagnosis of the underlying cause is critical in order to initiate adequate treatment.

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