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Introducción: la capacidad física de trabajo (CFT) se describe como el conjunto de tareas utilizadas para llevar a cabo las actividades de la vida diaria comparada con individuos sanos; incluye fuerzas de agarre y de abdomen, equilibrio, flexibilidad, velocidad de marcha y capacidad aeróbica. Por eso la CFT y el índice de masa muscular esquelético (IMME) tienen relación entre sí y son susceptibles de mejorar si se realiza entrenamiento físico. Objetivo: determinar si un programa de entrenamiento supervisado y controlado una vez a la semana durante seis meses es efectivo para cambiar la CFT y el IMME en sujetos mayores de 18 años. Métodos: estudio observacional, analítico, de cohorte retrospectiva, de 565 pacientes que asistieron a un programa de entrenamiento supervisado y controlado una vez a la semana durante seis meses. Resultados: hay mejoría de la media de la CFT en -8.59 puntos al finalizar la intervención (P=0.000) y aumento del IMME en -0.06 puntos (P=0.002). Conclusiones: este estudio sugiere que una intervención de una hora guiada y supervisada una vez a la semana durante seis meses brinda beneficios en variables de la CFT con mejoría del IMME, que se explica por cambios en la microestructura muscular (mejoría en la capacidad de realizar un trabajo por unidad de masa muscular).
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