Cómo citar
Becerra Urrego, R., & Galvis Rincón, J. C. (2011). Perfil hormonal del envejecimiento muscular. Revista Repertorio De Medicina Y Cirugía, 20(4), 217-224. https://doi.org/10.31260/RepertMedCir.v20.n4.2011.772

Autores/as

Rodrigo Becerra Urrego
Juan Carlos Galvis Rincón

Resumen

El concepto de sarcopenia implica la pérdida de la masa y la fuerza musculares asociadas con el envejecimiento. Se produce por múltiples factores, como el daño oxidativo, pérdida de unidades motoras alfa de la médula espinal, disminución de la calidad y masa musculares, descenso de hormonas anabólicas como dehidroepiandrosterona, testosterona, estrógenos, hormona del crecimiento, factor de crecimiento ligado a la insulina tipo IGF-1, hormona paratiroidea e insulina, así como aumento de diferentes interleuquinas y del cortisol, inactividad física voluntaria y dieta hipocalórica. En esta revisión analizamos el papel de algunas hormonas que afectan el balance dinámico entre estímulos anabólicos y catabólicos en el músculo y la relación entre estos cambios hormonales y el desarrollo de sarcopenia.

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Fundación Universitaria de Ciencias de la Salud - FUCS
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revista.repertorio@fucsalud.edu.co
Fundación Universitaria de Ciencias de la Salud - FUCS
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Tel: (+571) 3538100 Ext. 2836


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