Results of penetrating keratoplasty performed at the Hospital of San José
Resultados de queratoplastias penetrantes realizadas en el Hospital de San José
Show authors biography
OBJECTIVE: To evaluate the postoperative results of penetrating keratoplasty in patients operated in the Hospital of San José during a period of 5 years.
METHODS: A retrospective analytical study was carried out, in which the clinical histories of all patients who underwent penetrating keratoplasty at the Hospital de San José, in the period between January 1996 and July 2001, were reviewed. clinical histories that met previously established selection criteria.
RESULTS: 75 clinical records were reviewed, of which 62 met the inclusion criteria. Sixty-six corneal transplants were performed in 62 patients. 44 were men and 18 women, with an average age of 43.95 years. The most common indications were keratoconus (42.9%), leucoma (28.3%), pseudophakic and aphakic biillose keratopathy (19%), and less frequent were marginal pellucid degeneration (3.2%) and active corneal ulcers ( 6.3%) The visual acuity improvement in lines was between +10 and -2 with an average improvement of + 3.11 lines of visual acuity. There was immunological rejection to the graft on one occasion in 31.7% of the cases.
CONCLUSION: Penetrating keratoplasty is a safe and effective procedure in the recovery of vision in many cases of significant limitation of it, thanks to advances in surgical techniques and better pharmacological control of immunological rejections. In this study, a correlation was found between the highest score of risk factors for rejection and their presence. 84.2% of the patients improved at least one line of visual acuity.
Article visits 195 | PDF visits 564
1. Castroviejo R. Atlas de queratectomías y queratoplastias, Primera Edición, Barcelona, Salvat Editores, S.A, 1964, 3-446.
2. American Academic of Ophthalmology. Basic and Clinical Science Course. External Disease and Cornea. Section 8. p: 414- 433.
3. Mejía LF, Abad JC. Córnea y enfermedades externas. En: Arango K, Mejía LF, Abad JC. Fundamentos de cirugía oftalmología. Primera Edición, Medellín, Quebecor World. Bogotá 2001; 92-132.
4. Hill JC, Maske R, Watson P. Corticosteroids in corneal graft rejection. Oral versus single pulse therapy. Ophthalmology 1991; 98: 329-33.
5. Inoue K, Kimura C, Amano S, Sato T, Fujita N, Kagaya F, Kaji Y, Tsuru T, Araie M. Long-term outcome of systemic cyclosporine treatment following penetrating keratoplasty. Jpn J Ophthalmol 2001; 45:378-82.
6. Hill JC: The use of cyclosporine in high-risk keratoplasty. Am J Ophthalrnol 1989; 107: 506-10.
7. Jacobs J, Taravella M. Corneal Graft Rejection. eMedicine Journal 2001, 2 (1). www.emedicine.com
8. Wilson SE, Kaufman HE. Graft failure after penetrating keratoplasty. Surv Ophthalmol 1990; 34: 325-56.
9. Frucht-Pery J, Shtibel H, Solomon A, Siganos CS, Yassur Y, Pe' er J. Thirty years of penetrating keratoplasty in Israel. Cornea 1997; 16:16-20.
10. Legeais JM, Parc C, d'Hermies F, Pouliquen Y, Renard G. Nineteen years of penetrating keratoplasty in the Hotel-Dieu Hospital in Paris. Cornea. 2001; 20: 603-6.
11. Mamalis N, Anderson CW, Kreisler KR, Lundergan MK, Olson RJ. Changing trends in the indications for penetrating keratoplasty. Arch Ophthalmol 1992; 110: 1409-11.
12. Maumenee AE: The influence of donor - recipient sensitization on corneal grafts. Am J Ophthalmol 1951; 34: 142- 152.
13. Khodadoust AA, Silverstein AM. Transplantation and rejection of individual layers of the cornea. En: Investigative Ophthalmologic and Visual Sciences. 1997. pag 180-195.
14. Inoue K, Amano S, Oshika T, Tsuru T. Risk factors for corneal graft failure and rejection in penetrating keratoplasty. Acta Ophthalmol Scand 2001; 79: 251-5.
15. Naacke HG, Borderie VM, Bourcier T, Touzeau O, Moldovan M, Laroche L. Outcome of Corneal transplantation rejection. Cornea 2001; 20: 350-3. Dobbins KR, Price FW Jar, Whitson WE. Trends in the indications for penetrating keratoplasty in the midwestern United States. Cornea 2000;19: 813-6.