Clinical characteristics of patients with fractures for fragility

Características clínicas de los pacientes con fracturas por fragilidad

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Adriana Medina
Alejandra Rivera
Karina Bautista
Alejandra Alvarado

Abstract


Introduction: the prevalence of osteoporosis increases with aging, as well as, morbidity and mortality secondary to fragility fractures, impacting costs of healthcare. New strategies have enhanced fragility fractures detection and management. Objective: to describe the clinical features of patients with fragility fractures and their management at Hospital de San José, Bogotá, from February 2015 to July 2016, after establishing a fracture identification and prevention program. Methods: a cross sectional descriptive study. Clinical records of patients diagnosed with severe osteoporosis were reviewed. Demographic and clinical characteristics and treatment outcomes were analyzed. Results: out of 621 patients with osteoporosis-related fractures, 184 met the inclusion criteria. Mean age was 71.5 years (SD: 11.6). Fractures affected the distal radius in 36%, vertebrae in 34%, proximal femur in 18% and other sites in 11%. Osteoporosis was diagnosed in 30% of patients of which 30% received complete treatment for osteoporosis prior to fracture and 57.6% after fracture. Conclusions: fragility fractures are usually associated with osteoporosis, although there is underdiagnosis and under-treatment. Prevention of a future fracture is reflected in the increasing number of patients who received appropriate treatment, demonstrating the need to create education programs.

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References

1. Van Staa TP, Dennison EM, Leufkens HG, Cooper C. Epidemiology of fractures in England and Wales. Bone. 2001;29(6):517-22. Epub 2001/12/01.
2. [Guidelines for the diagnosis, prevention and treatment of osteoporosis. Italian Osteoporosis, Mineral Metabolism, and Skeletal Diseases Society]. Minerva Endocrinol. 2013;38(1 Suppl 1):1-30. Epub 2013/05/01. Linee Guida per la Diagnosi, Prevenzione e Terapia dell'Osteoporosi.
3. Lyles KW, Colon-Emeric CS, Magaziner JS, Adachi JD, Pieper CF, Mautalen C, et al. Zoledronic acid and clinical fractures and mortality after hip fracture. N Engl J Med. 2007;357(18):1799- 809. Epub 2007/09/20.
4. van den Bergh JP, van Geel TA, Geusens PP. Osteoporosis, frailty and fracture: implications for case finding and therapy. Nat Rev Rheumatol. 2012;8(3):163-72. Epub 2012/01/18.
5. Machado J. AV, Mondragón Á., Jiménez CE. Baja Frecuencia de Prescripción de profilaxis para osteoporosis en pacientes en tratamiento crónico con corticoides en Colombia. Rev Peru Med Exp Salud Publica. 2013;30(1):26–30.
6. Akesson K, Marsh D, Mitchell PJ, McLellan AR, Stenmark J, Pierroz DD, et al. Capture the Fracture: a Best Practice Framework and global campaign to break the fragility fracture cycle. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA. 2013;24(8):2135- 52. Epub 2013/04/17.
7. Dell R. Fracture prevention in Kaiser Permanente Southern California. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA. 2011;22 Suppl 3:457-60. Epub 2011/08/24.
8. Clark P, Cons-Molina F, Deleze M, Ragi S, Haddock L, Zanchetta JR, et al. The prevalence of radiographic vertebral fractures in Latin American countries: the Latin American Vertebral Osteoporosis Study (LAVOS). Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA. 2009;20(2):275-82. Epub 2008/06/28.
9. Marsh D, Akesson K, Beaton DE, Bogoch ER, Boonen S, Brandi ML, et al. Coordinator-based systems for secondary prevention in fragility fracture patients. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA. 2011;22(7):2051-65. Epub 2011/05/25.
10. Hernlund E, Svedbom A, Ivergard M, Compston J, Cooper C, Stenmark J, et al. Osteoporosis in the European Union: medical management, epidemiology and economic burden. A report prepared in collaboration with the International Osteoporosis Foundation (IOF) and the European Federation of Pharmaceutical Industry Associations (EFPIA). Archives of osteoporosis. 2013;8:136. Epub 2013/10/12.
11. The Latin American Regional Audit: epidemiology, costs & burden of osteoporosis in 2012. International Osteoporosis Foundation. 2012;1:1-68.
12. Nakayama A, Major G, Holliday E, Attia J, Bogduk N. Evidence of effectiveness of a fracture liaison service to reduce the re- fracture rate. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA. 2016;27(3):873-9. Epub 2015/12/10.
13. Mitchell P, Akesson K, Chandran M, Cooper C, Ganda K, Schneider M. Implementation of Models of Care for secondary osteoporotic fracture prevention and orthogeriatric Models of Care for osteoporotic hip fracture. Best Pract Res Clin Rheumatol. 2016;30(3):536-58. Epub 2016/11/26.
14. Huntjens KM, van Geel TA, van den Bergh JP, van Helden S, Willems P, Winkens B, et al. Fracture liaison service: impact on subsequent nonvertebral fracture incidence and mortality. J Bone Joint Surg Am. 2014;96(4):e29. Epub 2014/02/21.

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