Cross-sectional cohort study on residual renal function on hemodyálisis patients Hospital de San José. Bogotá DC, Colombia

Función renal residual en hemodiálisis: estudio de corte transversal hospital de San José. Bogotá DC, Colombia

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María Elvira Martínez
Magda Jeannette Alba
Diana Marcela Cifuentes
Isabel del Pilar Niño
Luz Dary Pedraza
Liliana Carolina Ramfrez
Eylen Rodríguez
Kennith Johana Tovar

Abstract

Residual renal function (RRF) preservation has proven to be an independent predictor of survival in peritoneal dialysis patients. Little information exists on its impact on hemodyalisis (HD). Objective: to describe RRF prevalence in chronic HD patients. Method: cross-sectional study conducted on June 2010. RRF was defined as a urine volume >100 mi during the long inter-dialysis interval. The glomerular filtration rate was calculated as the mean urea to creatinine clearance ratio. The statistic analysis was performed using STATA 10. Results: the study included 121 patients, mean age 58.3 years (SD 14.6), 66.9% men; 47.9 had preserved RRF, the mean time on HD was 52 months (IQR 16-101); 8.4% patients had received HD during more than five years and showed a median urine volume of 750 mi (IQR 400-1300). Weight gain in the inter-dialysis period was smaller in patients with preserved RRF (24.1 % vs. 46.7% with unpreserved RRF). Patients with preserved RRF required less ultrafiltration, had few hypotension episodes (22.4% vs. 27%) and a low incidence of hyperkalemia (20.7% vs. 30.1%) and hyperphosphatemia (51.7% vs. 58.7%). Conclusion: although these results are provided by a cross-sectional study it allows showing the hemodynamic and metabolic benefits furnished by a preserved RRF. Adequate urine volumes were documented in some patients receiving HD for a prolonged period of time. RRF preservation and urinary measuring are emphasized in patients on HD.

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