Biología feromonal en la especie humana
Pheromonal biology in the human species
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García, G. A., & Gaitán, Álvaro A. (2008). Biología feromonal en la especie humana. Revista Repertorio De Medicina Y Cirugía, 17(2), 72–89. https://doi.org/10.31260/RepertMedCir.v17.n2.2008.501
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Las funciones de quimiosensitividad y quimiosensorialidad de la nariz humana han sido siempre despreciadas, pero el incremento de evidencias a partir de investigaciones en otras especies animales sugiere que la olfación puede servir para otros propósitos muy importantes. En mamíferos está mediada por distintos órganos localizados en la cavidad nasal, como el epitelio olfatorio que une moléculas volátiles, responsable de la percepción consciente de olores y el órgano vomeronasal (OVN) que une feromonas y origina varias respuestas sobre todo entre individuos de una misma especie. Moléculas olorosas y feromonas se unen a receptores que permiten la señal de transducción, que son codificados por grandes familias multigénicas. Esta revisión presenta la información reciente y actualizada acerca de la temática de feromonas humanas. Abreviaturas: OVN, órgano vomeronasal; FM, feromona(s); NE, neurona(s).
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Referencias
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2. Proust M. En busca del Tiempo Perdido. Madrid: Alianza; 1992.
3. Cuevas C. El pensamiento del Islam. Madrid: Istmo; 1972.
4. Süskind P. El Perfume: historia de un asesino. Barcelona: Seix Banal; 2006.
5. Nobel Foundation [página en Intenet]. Stockholm: The Foundation; c2008 [citado 4 Oct 2007]. The Nobel Prize in Physiology or Medicine 2004; [aprox. 2 pantallas]. Disponible en: http://nobelprize.org/nobel_prizes/medicine/laureates/2004/
6. Berliner DL, Jennings-White C, Lavker RM. The human skin: fragrances and pheromones. J Steroid Biochem Mol Biol. 1991 Oct;39(4B):671-9
7. Stensaas LJ, Lavker RM, Monti-Bloch L, Grosser BI, Berliner DL. Ultrastructure of the human vomeronasal organ. J Steroid Biochem Mol Biol. 1991 Oct;39(4B):553-60.
8. Wilson E0. Sociobiology: the new synthesis. Cambridge: Harvard University Press; 1975.
9. Boch R, Shearer DA, Stone BC. Identification of isoamyl acetate as an active component in the sting pheromone of the honey bee. Nature. 1962 Sep 8;195:1018-20
10. Callow JA, Callow ME. Biofilms. Prog Mol Subcell Biol 2006;42:141-69.
11. Tittiger C. Functional genomics and insect chemical ecology. J Chem Ecol. 2004 Dec;30(12):2335-58
12. National Center for Biotechnology Information [página en Intenet]. Bethesda: The Center; c2008 [actualizado 14 Abr 2008; citado 4 Oct 2007]. Mesh; [aprox. 2 pantallas]. Disponible en: http://www.ncbi.nlm.nih.gov/sites/entrez? db=mesh
13. Ledford H. Plant biology: the flower of seduction. Nature. 2007 Feb 22;445(7130):816-7
14. Sachs JL, Mueller UG, Wilcox TP, Bull JJ. The evolution of cooperation. Q Rev Biol. 2004 Jun;79(2):135-60
15. Sumpter DJ. The principies of collective animal behaviour. Philos Trans R Soc Lond B Biol Sci. 2006 Jan 29;361 (1465):5-22
16. Apfelbach R, Blanchard CD, Blanchard RJ, Hayes RA, McGregor IS. The effects of predator odors in mammafian prey species: a review of field and laboratory studies. Neurosci Biobehav Rev. 2005;29(8):1123-44.
17. Takahashi LK, Nakashima BR, Hong H, Watanabe K. The smell of danger: a behavioral and neural analysis of predator odor-induced fear. Neurosci Biobehav Rev. 2005;29(8): 1157-67.
18. Sbarbati A, Osculati F. Allelochemical communication in vertebrates: kairomones, allomones and synomones. Cells Tissues Organs. 2006;183(4):206-19.
19. Brennan PA, Zufall F. Pheromonal communication in vertebrates. Nature. 2006 Nov 16;444(7117):308-15.
20. Brennan PA, Kendrick KM. Mammalian social odours: attraction and individual recognition. Philos Trans R Soc Lond B Biol Sci. 2006 Dec 29;361(1476):2061-78.
21. Smith TD, Bhatnagar KP, Shimp KL, Kinzinger JH, Bonar CJ, Burrows AM, Mooney MP, Siegel MI. Histological definition of the vomeronasal organ in humans and chimpanzees, with a comparison to other primates. Anat Rec. 2002 Jun 1;267(2):166-76.
22. Evans CS. Accessory chemosignaling mechanisms in primates. Am J Primatol. 2006 Jun;68(6):525-44.
23. Mundy NI. Genetic basis of olfactory communication in primates. Am J Primatol. 2006 Jun;68(6):559-67.
24. Snowdon CT, Ziegler TE, Schultz-Darken NJ, Ferris CF. Social odours, sexual arousal and pairbonding in primates. Philos Trans R Soc Lond B Biol Sci. 2006 Dec 29;361(1476):2079-89.
25. Nagasawa H, Kuniyoshi H, Arima R, Kawano T, Ando T, Suzuki A. Structure and activity of Bombyx PBAN. Arch Insect Biochem Physiol. 1994;25(4):261-70.
26. Breer H, Fleischer J, Strotmann J The sense of smell: multiple olfactory subsystems. Cell Mol Life Sci. 2006 Jul;63(13):1465-75.
27. Witt M, Hummel T. Vomeronasal versus olfactory epithelium: is there a cellular basis for human vomeronasal perception? Int Rev Cytol 2006;248:209-59.
28. Bhatnagar KP, Smith TD. The human vomeronasal organ. V. An interpretation of its discovery by Ruysch, Jacobson, or Kolliker, with an English translation of Kolliker (1877). Anat Rec B New Anat. 2003 Jan;270(1):4-15.
29. Eisthen HL, Wyatt TD. The vomeronasal system and pheromones. Curr Biol. 2006 Feb 7;16(3):R73-4.
30. Witt M, Wozniak W. Structure and function of the vomeronasal organ. Adv Otorhinolaryngol. 2006;63:70-83.
31. Grus WE, Zhang J. Origin and evolution of the vertebrate vomeronasal system viewed through system-specific genes. Bioessays. 2006 Jul;28(7):709-18.
32. Abolmaali ND, Kühnau D, Knecht M, Kühler K, Hüttenbrink KB, Hummel T. Imaging of the human vomeronasal duct. Chem Senses 2001;26:35-9.
33. Knecht M, Lundstróm JN, Witt M, Hüttenbrink KB, Heilmann S, Hummel T. Assessment of olfactory function and androstenone odor thresholds in humans with or without functional occlusion of the vomeronasal duct. hav Neurosci. 2003 Dec;117(6):1135-41.
34. Radlanski RJ, Emmerich S, Renz H. Prenatal morphogenesis of the human incisive canal. Anat Embryol (Berl). 2004 Jul;208(4):265-71.
35. Wysocki CJ, Preti G. Facts, fallacies, fears, and frustrations with human pheromones. Anat Rec A Discov Mol Cell Evol Biol. 2004 Nov;281(1):1201-11.
36. Bhatnagar KP, Smith TD, Winstead W. The human vomeronasal organ: part IV. Incidence, topography, endoscopy, and ultrastructure of the nasopalatine recess, nasopalatine fossa, and vomeronasal organ.Am J Rhinol. 2002 Nov-Dec ;16(6):343-50.
37. Witt M, Georgiewa B, Knecht M, Hummel T. On the chemosensory nature of the vomeronasal epithelium in adult humans. Histochem Cell Biol. 2002 Jun;117(6):493-509.
38. Smith TD, Bhatnagar KP. The human vomeronasal organ. Part II: prenatal development.J Anat. 2000 Oct;197 Pt 3 :421-36.
39. Bhatnagar KP, Smith TD. The human vomeronasal organ. III. Postnatal development from infancy to the ninth decade. J Anat. 2001 Sep;199(Pt 3):289-302.
40. Schober JM, Pfaff D. The neurophysiology of sexual arousal. Best Pract Res Clin Endocrinol Metab 2007;21:445-61.
41. Bhutta MF. Sex and the nose: human pheromonal responses. J R Soc Med. 2007 Jun;100(6):268-74.
42. Sigerist H. Hitos en la historia de la salud pública. 5'. ed. Madrid: Siglo XXI; 1998.
43. Grosser BI, Monti-Bloch L, Jennings-White C, Berliner DL. Behavioral and electrophysiological effects of androstadienone, a human pheromone. Psychoneuroendocrinolo . 2000 Apr;25(3):289-99.
44. Wysocki CJ, Beauchamp GK.Ability to smell androstenone is genetically determined. Proc Natl Acad Sci U S A. 1984 Aug;81(15):4899-902.
45. Wysocki CJ, Dorries KM, Beauchamp GK. Ability to perceive androstenone can be acquired by ostensibly anosmic people. Proc Natl Acad Sci USA. 1989 Oct;86(20):7976-8.
46. Jahanfar S, Awang CH, Rahman RA, Samsuddin RD, See CP. Is 3alpha-androstenol pheromone related to menstrual synchrony? J Fam Plann Reprod Health Care. 2007 Apr;33(2): 116-8.
47.Cutler WB, Genovese E. Pheromones, sexual attractiveness and quality of life in menopausal women. Climacteric. 2002 Jun;5(2):112-21.
48. McCoy NL, Pitino L.Pheromonal influences on sociosexual behavior in young women.Physiol Behav. 2002 Mar;75(3):367-75.
49. Thome F, Neave N, Scholey A, Moss M, Fink B. Effects of putative male pheromones on female ratings of male attractiveness: influence of oral contraceptives and the menstrual cycle. Neuro Endocrinol Lett. 2002 Aug;23(4):291-7.
50. Friebely J, Rako S. Pheromonal influences on sociosexual behavior in postmenopausal women. J Sex Res. 2004 Nov;41(4):372-80.
51. Villemure C, Bushnell MC. The effects of the steroid androstadienone and pleasant odorants on the mood and pain perception of men and women. Eur J Pain. 2007 Feb;11(2):181-91.
52. Berglund H, Lindstróm P, Savic I. Brain response to putative pheromones in lesbian women. Proc Natl Acad Sci U S A. 2006 May 23;103(21):8269-74.
53. Martins Y, Preti G, Crabtree CR, Runyan T, Vainius AA, Wysocki CJ. Preference for human body odors is influenced by gender and sexual orientation. Psychol Sci. 2005 Sep ;16(9): 694-701.
54. Flower DR. The lipocalin protein family: a role in cell regulation.FEBS Lett. 1994 Oct 31;354(1):7-11.
55. García GA, Clavijo D, Mejía O, García A, Vittorino M, Casadiego C, Hernández S, Cobos C, Tovar J, Rey C, Zamudio C. Aspectos biomédicos de la familia de las lipocalinas. Universitas Médica. 2007 Abr;48(2) :118-28.
56. Briand L, Eloit C, Nespoulous C, Bézirard V, Huet JC, Henry C, Blon F, Trotier D, Pernollet JC. Evidence of an odorant-binding protein in the human olfactory mucus: location, structural characterization, and odorant-binding properties. istry. 2002 Jun 11 ;41(23): 7241 -52.
57. Beynon RJ, Hurst JL. Urinary proteins and the modulation of chemical scents in mice and rats. Peptides. 2004 Sep ;25(9): 1553-63 .
58. Briand L, Trotier D, Pernollet JC. Aphrodisin, an aphrodisiac lipocalin secreted in hamster vaginal secretions. Peptides. 2004 Sep;25(9):1545-52.
59. Sbarbati A, Osculati F. A new fate for old cells: brush cells and related elements. Anat. 2005 Apr;206(4):349-58.
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