Harlequin Ichthyosis, one devastating genodermatosis

Ictiosis arlequín, una genodermatosis devastadora

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Felisa B Carvajalino
Laura F Peña

Abstract


Harlequin ichthyosis is the most severe and aggressive presentation of congenital ichthyosis. It is an extremely rare autosomal recessive genetic disorder with a fatal outcome in most cases; harlequin infants usually die in the first few days of life secondary to infection and dehydration among other complications. Prenatal diagnosis remains difficult and adequate care may enhance survival. We report a female harlequin infant born to a mother with a history of harlequin fetus.

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References

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